Spontaneous liver rupture after treatment with drug-eluting beads

C. O. Ritter*, M. Wartenberg, A. Mottok, U. Steger, J. P. Goltz, D. Hahn, R. Kickuth

*Corresponding author for this work
7 Citations (Scopus)


Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

Original languageEnglish
JournalCardioVascular and Interventional Radiology
Issue number1
Pages (from-to)198-202
Number of pages5
Publication statusPublished - 01.02.2012


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