Spontaneous liver rupture after treatment with drug-eluting beads

C. O. Ritter; M. Wartenberg; A. Mottok; U. Steger; J. P. Goltz; D. Hahn; R. Kickuth

doi:10.1007/s00270-011-0145-7

Spontaneous liver rupture after treatment with drug-eluting beads

C. O. Ritter^*, M. Wartenberg, A. Mottok, U. Steger, J. P. Goltz, D. Hahn, R. Kickuth

^*Corresponding author for this work

Clinic of Radiology and Nuclear Medicine

University of Würzburg

7 Citations (Scopus)

Abstract

Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

Original language	English
Journal	CardioVascular and Interventional Radiology
Volume	35
Issue number	1
Pages (from-to)	198-202
Number of pages	5
ISSN	0174-1551
DOIs	https://doi.org/10.1007/s00270-011-0145-7
Publication status	Published - 01.02.2012

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abstract = "Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.",

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AU - Ritter, C. O.

AU - Wartenberg, M.

AU - Mottok, A.

AU - Steger, U.

AU - Goltz, J. P.

AU - Hahn, D.

AU - Kickuth, R.

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

AB - Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

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M3 - Journal articles

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SN - 0174-1551

VL - 35

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EP - 202

JO - CardioVascular and Interventional Radiology

JF - CardioVascular and Interventional Radiology

IS - 1

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Spontaneous liver rupture after treatment with drug-eluting beads

Abstract

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