Abstract
Maximum information density: The complete hexanucleotide sequence space can be immobilized on a chip. The binding of a number of proteins was profiled with this array of 4096 sequences, including fluorescently labeled forms of the HIV-2 and HIV-1 reverse transciptases (the consensus motif is shown in the picture). This new technique should aid in the search for pharmaceutical lead compunds.
| Original language | English |
|---|---|
| Journal | Angewandte Chemie - International Edition |
| Volume | 50 |
| Issue number | 5 |
| Pages (from-to) | 1052-1054 |
| Number of pages | 3 |
| ISSN | 1433-7851 |
| DOIs | |
| Publication status | Published - 01.02.2011 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Fingerprint
Dive into the research topics of 'Specific recognition of proteins by array-bound hexanucleotides'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver