Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA

Jürgen Eggers, Günter Seidel*, Björn Koch, Inke R. König

*Corresponding author for this work
96 Citations (Scopus)


The authors studied the effect of transcranial ultrasound on patients with acute middle cerebral artery occlusion and contraindications for thrombolysis. Fifteen consecutive subjects were randomized for insonation over 1 hour or for inclusion in a control group. By day 4, recanalization and neurologic improvement occurred more frequently in the target group. Ultrasound-induced acceleration of clot dissolution may be an option for patients with contraindications for recombinant tissue plasminogen activator.

Original languageEnglish
Issue number6
Pages (from-to)1052-1054
Number of pages3
Publication statusPublished - 22.03.2005


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