Sometimes Intermediates Do the Job!

Rolf Hilgenfeld*, Ksenia Pumpor

*Corresponding author for this work
3 Citations (Scopus)


The SARS coronavirus main proteinase is a prime target for antiviral therapy. In this issue of Chemistry & Biology, Wu et al. describe potent inhibition of the enzyme by benzotriazole esters, which were originally obtained as intermediates in the synthesis of lopinavir derivatives [1].

Original languageEnglish
JournalChemistry and Biology
Issue number3
Pages (from-to)235-236
Number of pages2
Publication statusPublished - 01.03.2006

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

Coronavirus related work

  • Research on SARS-CoV-2 / COVID-19


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