The SARS coronavirus main proteinase is a prime target for antiviral therapy. In this issue of Chemistry & Biology, Wu et al. describe potent inhibition of the enzyme by benzotriazole esters, which were originally obtained as intermediates in the synthesis of lopinavir derivatives .
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
Coronavirus related work
- Research on SARS-CoV-2 / COVID-19