Sleep disturbances in lung cancer patients assigned to definitive or adjuvant irradiation

Dirk Rades*, Svenja Kopelke, Soeren Tvilsted, Troels W. Kjaer, Steven E. Schild, Tobias Bartscht

*Corresponding author for this work
1 Citation (Scopus)


Background/Aim: A considerable number of patients with lung cancer are scheduled for definitive or adjuvant radiotherapy. Prevalence and potential risk factors of preradiotherapy sleep disturbances were evaluated. Patients and Methods: Nineteen factors were retrospectively investigated for associations with pre-radiotherapy sleep disturbances in 77 lung cancer patients. Factors included COVID-19 pandemic; age; gender; performance score; comorbidity index; history of another malignancy; distress score; number of emotional, physical or practical problems; patient's request for psychological support; histology; tumor stage; upfront surgery; chemotherapy; and type of radiotherapy. Results: Thirty-one patients (40.3%) reported sleep disturbances that were significantly associated with distress score 6-10 (p=0.019), ≥2 emotional problems (p=0.001), ≥5 physical problems (p<0.001), and request for psychological support (p=0.006). Trends were found for female gender (p=0.064) and stereotactic body radiation therapy (p=0.057). Conclusion: Many lung cancer patients assigned to radiotherapy reported sleep disturbances. Risk factors can be used to identify patients in need of psychological support already before treatment.

Original languageEnglish
JournalIn Vivo
Issue number6
Pages (from-to)3333-3337
Number of pages5
Publication statusPublished - 12.2021

Research Areas and Centers

  • Centers: University Cancer Center Schleswig-Holstein (UCCSH)
  • Research Area: Luebeck Integrated Oncology Network (LION)


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