TY - JOUR
T1 - Sleep deprivation induces fragmented memory loss
AU - Ashton, Jennifer E.
AU - Harrington, Marcus O.
AU - Langthorne, Diane
AU - Ngo, Hong Viet V.
AU - Cairney, Scott A.
N1 - Funding Information:
This work was supported by Medical Research Council (MRC) Career Development Award (MR/P020208/1) to S.A.C. We are very grateful to two anonymous reviewers for their helpful comments on an earlier version of this manuscript.
Publisher Copyright:
© 2020 Ashton et al. This article, published in Learning & Memory, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4
Y1 - 2020/4
N2 - Sleep deprivation increases rates of forgetting in episodic memory. Yet, whether an extended lack of sleep alters the qualitative nature of forgetting is unknown. We compared forgetting of episodic memories across intervals of overnight sleep, daytime wakefulness, and overnight sleep deprivation. Item-level forgetting was amplified across daytime wakefulness and overnight sleep deprivation, as compared to sleep. Importantly, however, overnight sleep deprivation led to a further deficit in associative memory that was not observed after daytime wakefulness. These findings suggest that sleep deprivation induces fragmentation among item memories and their associations, altering the qualitative nature of episodic forgetting.
AB - Sleep deprivation increases rates of forgetting in episodic memory. Yet, whether an extended lack of sleep alters the qualitative nature of forgetting is unknown. We compared forgetting of episodic memories across intervals of overnight sleep, daytime wakefulness, and overnight sleep deprivation. Item-level forgetting was amplified across daytime wakefulness and overnight sleep deprivation, as compared to sleep. Importantly, however, overnight sleep deprivation led to a further deficit in associative memory that was not observed after daytime wakefulness. These findings suggest that sleep deprivation induces fragmentation among item memories and their associations, altering the qualitative nature of episodic forgetting.
UR - http://www.scopus.com/inward/record.url?scp=85082021205&partnerID=8YFLogxK
U2 - 10.1101/lm.050757.119
DO - 10.1101/lm.050757.119
M3 - Journal articles
C2 - 32179655
AN - SCOPUS:85082021205
SN - 1072-0502
VL - 27
SP - 130
EP - 135
JO - Learning and Memory
JF - Learning and Memory
IS - 4
ER -
