Skin cancer screening participation and impact on melanoma incidence in Germany-an observational study on incidence trends in regions with and without population-based screening

A. Waldmann*, S. Nolte, M. A. Weinstock, E. W. Breitbart, N. Eisemann, A. C. Geller, R. Greinert, B. Volkmer, A. Katalinic

*Corresponding author for this work
62 Citations (Scopus)

Abstract

Background: The SCREEN (Skin Cancer Research to provide Evidence for Effectiveness of Screening in Northern Germany) project involved population-wide skin cancer screening with whole-body examination by general physicians and dermatologists. It was conducted in the German state of Schleswig-Holstein (July 2003-June 2004), but not in the German state of Saarland. Methods: The population-based registries of Schleswig-Holstein and Saarland provided data on melanoma incidence before, during, and after SCREEN to assess the association of skin cancer screening with incidence.Results:Approximately 19% of the Schleswig-Holstein population participated in SCREEN (women: 27%, men: 10%). A total of 52% of all melanomas diagnosed during SCREEN in Schleswig-Holstein were detected as part of the project. Melanoma incidence increased during SCREEN (invasive melanoma in women: 8.9 per 100 000 (95% confidence intervals (CI): 6.1; 11.7); men: +4.0 per 100 000 (95% CI:-1.6; 6.4)) and decreased afterwards (women: 10.6 per 100 000 (95% CI:-13.3; 7.9); men: 4.1 per 100 000 (95% CI:-6.5; 1.7)). Similar changes were not observed in Saarland that had no such project. The differences between the two states were greatest among women, the group with the greater SCREEN participation. Conclusion: The SCREEN project had a substantial impact on melanoma incidence. This is consistent with the impact of effective screening for other cancers.

Original languageEnglish
JournalBritish Journal of Cancer
Volume106
Issue number5
Pages (from-to)970-974
Number of pages5
ISSN0007-0920
DOIs
Publication statusPublished - 28.02.2012

Research Areas and Centers

  • Research Area: Center for Population Medicine and Public Health (ZBV)

DFG Research Classification Scheme

  • 205-02 Public Health, Health Services Research and Social Medicine
  • 205-14 Haematology, Oncology
  • 205-19 Dermatology

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