Skelett-typische Quervernetzungen im kollagenen Bindegewebe bei Dermatoliposklerose

Translated title of the contribution: Skeleton-typical cross-links in collagens in lipodermatosclerosis

J. Brinckmann*, Yahya Açil, M. Tronnier, B. Bätge, W. Schmeller, P. K. Müller, H. H. Wolff

*Corresponding author for this work
2 Citations (Scopus)

Abstract

Cross-links hetween collagen molecules are essential for the mechanical quality of connective tissue. The cross-links can be divided into skeletal and skin specific cross-links. We analyzed the cross-link pattern of lipodermatosclerosis (LDS) in eight patients. All skin specimens of a sclerotic area contained higher levels of HP and LP than normal controls. Specific disturbances in collagen synthesis are required for the generation of these cross-links in the pathogenesis of LDS.

Translated title of the contributionSkeleton-typical cross-links in collagens in lipodermatosclerosis
Original languageGerman
JournalPhlebologie
Volume25
Issue number5
Pages (from-to)193-196
Number of pages4
ISSN0939-978X
Publication statusPublished - 09.1996

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