Abstract
Cross-links hetween collagen molecules are essential for the mechanical quality of connective tissue. The cross-links can be divided into skeletal and skin specific cross-links. We analyzed the cross-link pattern of lipodermatosclerosis (LDS) in eight patients. All skin specimens of a sclerotic area contained higher levels of HP and LP than normal controls. Specific disturbances in collagen synthesis are required for the generation of these cross-links in the pathogenesis of LDS.
Translated title of the contribution | Skeleton-typical cross-links in collagens in lipodermatosclerosis |
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Original language | German |
Journal | Phlebologie |
Volume | 25 |
Issue number | 5 |
Pages (from-to) | 193-196 |
Number of pages | 4 |
ISSN | 0939-978X |
Publication status | Published - 09.1996 |