Silencing of the Y-chromosomal gene tspy during murine evolution

Stephanie Schubert, Frank Dechend, Britta Skawran, Bärbel Kunze, Heinz Winking, Carsten Weile, Irmgard Römer, Myriam Hemberger, Reinald Fundele, Tikaram Sharma, Jörg Schmidtke*

*Corresponding author for this work
12 Citations (Scopus)


We have studied the process of tspy gene silencing in murine evolution. We have isolated functional tspy sequences from Apodemus agrarius, A. sylvaticus, A. flavicollis, and Mus platythrix (subgenus Pyromys) and nonfunctional tspy sequences from species of the subgenus Mus. We present two alternative models as to how tspy may have lost its function in the murine lineage.

Original languageEnglish
JournalMammalian Genome
Issue number4
Pages (from-to)288-291
Number of pages4
Publication statusPublished - 2000

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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