Siderophore transport in mycobacteria analyzed by Mössbauer spectroscopy: Possible routes to novel antibiotics against these organisms?

B. F. Matzanke; U. Möllmann; R. Reissbrodt; V. Schünemann; A. X. Trautwein

doi:10.1023/A:1011053130791

Siderophore transport in mycobacteria analyzed by Mössbauer spectroscopy: Possible routes to novel antibiotics against these organisms?

B. F. Matzanke^*, U. Möllmann, R. Reissbrodt, V. Schünemann, A. X. Trautwein

^*Corresponding author for this work

Institute of Physics

6 Citations (Scopus)

Abstract

Iron uptake of the ⁵⁷Fe-siderophores ferricrocin, rhizoferrin and citrate in M. smegmatis was analyzed by in situ Mössbauer spectroscopy. Siderophore dependent uptake and metabolic utilization patterns of ⁵⁷Fe were found. Rhizoferrin is accumulated in the organism and, therefore, represents a suitable candidate for the synthesis of novel siderophore-antibiotics conjugates.

Original language	English
Journal	Hyperfine Interactions
Volume	112
Issue number	1-4
Pages (from-to)	123-128
Number of pages	6
ISSN	0304-3843
DOIs	https://doi.org/10.1023/A:1011053130791
Publication status	Published - 01.12.1998

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Cite this

@article{ae83769afd2d4ab8b3beee080a2d27d4,

title = "Siderophore transport in mycobacteria analyzed by M{\"o}ssbauer spectroscopy: Possible routes to novel antibiotics against these organisms?",

abstract = "Iron uptake of the 57Fe-siderophores ferricrocin, rhizoferrin and citrate in M. smegmatis was analyzed by in situ M{\"o}ssbauer spectroscopy. Siderophore dependent uptake and metabolic utilization patterns of 57Fe were found. Rhizoferrin is accumulated in the organism and, therefore, represents a suitable candidate for the synthesis of novel siderophore-antibiotics conjugates.",

author = "Matzanke, \{B. F.\} and U. M{\"o}llmann and R. Reissbrodt and V. Sch{\"u}nemann and Trautwein, \{A. X.\}",

year = "1998",

month = dec,

day = "1",

doi = "10.1023/A:1011053130791",

language = "English",

volume = "112",

pages = "123--128",

journal = "Hyperfine Interactions",

issn = "0304-3843",