Abstract

Absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue, i.e. a sub-micrometer scale displacement happens within a couple of microseconds. In this study, we initially investigate the depth-resolved deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. Functional images can be reconstructed based on the detected deformation, which enables a new imaging modality called thermo-elastic deformation imaging (TDI). Our results show that the associated displacement is related to the optical absorption of the short laser pulses. The TDI images can provide tissue type information in addition to the conventional OCT images.
Original languageEnglish
Title of host publicationOptical Interactions with Tissue and Cells XXVIII
EditorsHope Thomas Beier, E. Duco Jansen
Number of pages4
Volume10062
PublisherSPIE
Publication date15.02.2017
Pages100620C-100620C-4
ISBN (Print)978-151060565-7
DOIs
Publication statusPublished - 15.02.2017
EventSPIE BIOS
- San Francisco, United States
Duration: 28.01.201702.02.2017

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