TY - JOUR
T1 - Serum antibodies to klebsiella capsular polysaccharides in ankylosing spondylitis
AU - Sahly, Hany
AU - Podschun, Rainer
AU - Sass, Rainer
AU - Bröker, Barbara
AU - Kekow, Jörn
AU - Gross, Wolfgang Ludwig
AU - Ullmann, Uwe
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1994/5
Y1 - 1994/5
N2 - Objective. To measure antibodies to Klebsiella capsular polysaccharides in the sera of HLA–B27 positive patients with ankylosing spondylitis (AS), compared with HLA–B27 positive and HLA–B27 negative healthy control subjects. Methods. Antibodies were detected by means of an enzyme‐linked immunosorbent assay specific for each of the 77 known Klebsiella serotypes. Results. Significantly elevated frequencies and titers of antibodies to capsular polysaccharides K26, K36, and K50 were detected in sera from AS patients, compared with controls. Conclusion. These results suggest the predominance of Klebsiella serotypes K26, K36, and K50 in patients with AS.
AB - Objective. To measure antibodies to Klebsiella capsular polysaccharides in the sera of HLA–B27 positive patients with ankylosing spondylitis (AS), compared with HLA–B27 positive and HLA–B27 negative healthy control subjects. Methods. Antibodies were detected by means of an enzyme‐linked immunosorbent assay specific for each of the 77 known Klebsiella serotypes. Results. Significantly elevated frequencies and titers of antibodies to capsular polysaccharides K26, K36, and K50 were detected in sera from AS patients, compared with controls. Conclusion. These results suggest the predominance of Klebsiella serotypes K26, K36, and K50 in patients with AS.
UR - http://www.scopus.com/inward/record.url?scp=0028315881&partnerID=8YFLogxK
U2 - 10.1002/art.1780370521
DO - 10.1002/art.1780370521
M3 - Journal articles
C2 - 8185704
AN - SCOPUS:0028315881
SN - 0004-3591
VL - 37
SP - 754
EP - 759
JO - Arthritis & Rheumatism
JF - Arthritis & Rheumatism
IS - 5
ER -