Apart from the common gynaecological carcinomas there exist a large number of rare non-epithelial malignant tumours. In this context, ovarian stromal cell tumours account for 5% and germinal cell tumours of the ovary for 15% of ovarian neoplasms. Uterine sarcomas represent only 2-3% of all rare genital malignancies. The standard non-epithelial ovarian tumour therapy is in many cases a fertility-conserving operation. However, in advanced stages a debulking operation is required analogue to the therapy of ovarian tumours. In this situation adjuvant BEP chemotherapy with platinum should be carried out. The basic module in the treatment of uterine sarcomas calls for a radical operative procedure which can be followed up with post-operative platinum-based chemotherapy. In contrast gestational trophoblastic disease should primarily be treated by chemotherapy.