Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits

S Rasika; Ruben Nogueiras; Markus Schwaninger; Vincent Prevot

doi:10.1038/s41574-024-00955-3

Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits

S Rasika, Ruben Nogueiras, Markus Schwaninger, Vincent Prevot

Institute of Experimental and Clinical Pharmacology and Toxicology

3 Citations (Scopus)

Abstract

Gonadotropin-releasing hormone is implicated in cognitive functions, and its loss is a factor in pathological brain ageing. There are similarities between these processes and the neurological and cognitive deficits observed in patients with long COVID. Here, we explore the hypothesis that neuroanatomical and transcriptomic alterations associated with long COVID could stem from this neuroendocrine perturbation.

Original language	English
Journal	Nature Reviews Endocrinology
Volume	20
Issue number	4
Pages (from-to)	189-190
Number of pages	2
ISSN	1759-5029
DOIs	https://doi.org/10.1038/s41574-024-00955-3
Publication status	Published - 04.2024

Funding

Funders	Funder number
European Research Council ERC-Synergy-Grant-2019-WATCH	810331
Agence Nationale de la Recherche en Santé et la Fondation pour la Recherche Médicale	ECTZ200878
Horizon 2020	847941 miniNO

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

2.22-09 Pharmacology
2.22-17 Endocrinology, Diabetology, Metabolism
2.23-08 Human Cognitive and Systems Neuroscience

Coronavirus related work

Research on SARS-CoV-2 / COVID-19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/s41574-024-00955-3

Cite this

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abstract = "Gonadotropin-releasing hormone is implicated in cognitive functions, and its loss is a factor in pathological brain ageing. There are similarities between these processes and the neurological and cognitive deficits observed in patients with long COVID. Here, we explore the hypothesis that neuroanatomical and transcriptomic alterations associated with long COVID could stem from this neuroendocrine perturbation.",

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AU - Prevot, Vincent

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AB - Gonadotropin-releasing hormone is implicated in cognitive functions, and its loss is a factor in pathological brain ageing. There are similarities between these processes and the neurological and cognitive deficits observed in patients with long COVID. Here, we explore the hypothesis that neuroanatomical and transcriptomic alterations associated with long COVID could stem from this neuroendocrine perturbation.

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Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits

Abstract

Funding

Research Areas and Centers

DFG Research Classification Scheme

Coronavirus related work

UN SDGs

Access to Document

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Cite this