Abstract
A new approach for the detection of chromosome deletion 22q11.2 in interphase nuclei from buccal mucosa cells obtained by a non-invasive procedure is decribed. FISH analysis has been performed on samples from a group of 101 patients that presented consecutively for speech therapy and/or surgical correction of cleft palate. A normal result has been obtained in 98 patients; a deletion 22q11.2 was present in three patients (2.8%) with cleft palate.
Original language | English |
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Journal | International Journal of Oral and Maxillofacial Surgery |
Volume | 32 |
Issue number | 2 |
Pages (from-to) | 198-200 |
Number of pages | 3 |
ISSN | 0901-5027 |
DOIs | |
Publication status | Published - 2003 |