Skip to main navigation Skip to search Skip to main content

Sampling strategies for model free linkage analyses of quantitative traits: Implications for sib pair studies of reading and spelling disabilities to minimize the total study cost

Andreas Ziegler*

*Corresponding author for this work

Abstract

One approach to establish linkage is based on allele sharing methods for sib pairs. In recent years the use of selected sib pairs to increase power for mapping quantitative traits in humans has been discussed intensively. In this paper the different basic principles for sib pair sampling proposed in the literature are made evident. Implications for ascertainment schemes of sib pairs to minimize the total study cost in linkage analyses on reading and spelling disabilities are discussed.

Original languageEnglish
JournalEuropean Child and Adolescent Psychiatry
Volume8
Issue numberSUPPL. 3
Pages (from-to)35-39
Number of pages5
ISSN1018-8827
DOIs
Publication statusPublished - 1999

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Fingerprint

Dive into the research topics of 'Sampling strategies for model free linkage analyses of quantitative traits: Implications for sib pair studies of reading and spelling disabilities to minimize the total study cost'. Together they form a unique fingerprint.

Cite this