Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock: 1-Year Results of the ECLS-SHOCK Trial

Steffen Desch; Uwe Zeymer; Ibrahim Akin; Michael Behnes; Daniel Duerschmied; Tienush Rassaf; Amir Abbas Mahabadi; Ralf Lehmann; Ingo Eitel; Tobias Graf; Tim Seidler; Andreas Schuster; Tharusan Thevathasan; Carsten Skurk; Peter Clemmensen; Marcus Hennersdorf; Stephan Fichtlscherer; Ingo Voigt; Melchior Seyfarth; Stefan John; Sebastian Ewen; Axel Linke; Eike Tigges; Peter Nordbeck; Leonhard Bruch; Christian Jung; Jutta Franz; Philipp Lauten; Marko Noc; Georg Fuernau; Hans-Josef Feistritzer; Janine Pöss; Eva Kirchhof; Taoufik Ouarrak; Steffen Schneider; Anne Freund; Holger Thiele

doi:10.1093/eurheartj/ehae610

Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock: 1-Year Results of the ECLS-SHOCK Trial

Steffen Desch, Uwe Zeymer, Ibrahim Akin, Michael Behnes, Daniel Duerschmied, Tienush Rassaf, Amir Abbas Mahabadi, Ralf Lehmann, Ingo Eitel, Tobias Graf, Tim Seidler, Andreas Schuster, Tharusan Thevathasan, Carsten Skurk, Peter Clemmensen, Marcus Hennersdorf, Stephan Fichtlscherer, Ingo Voigt, Melchior Seyfarth, Stefan JohnSebastian Ewen, Axel Linke, Eike Tigges, Peter Nordbeck, Leonhard Bruch, Christian Jung, Jutta Franz, Philipp Lauten, Marko Noc, Georg Fuernau, Hans-Josef Feistritzer, Janine Pöss, Eva Kirchhof, Taoufik Ouarrak, Steffen Schneider, Anne Freund, Holger Thiele

Abstract

Extracorporeal life support (ECLS) has been increasingly used in the treatment of severe infarct-related cardiogenic shock in the last decade. The randomised ECLS-SHOCK trial demonstrated no benefit of early routine use on 30-day all-cause death. We herein present mid-term results. At 1-year follow-up, there were no significant differences in all-cause or cardiovascular mortality, neurologic outcome, recurrent myocardial infarction, repeat revascularisation and rehospitalisations for heart failure between ECLS and usual medical care.

Original language	English
Journal	European Heart Journal
ISSN	0195-668X
DOIs	https://doi.org/10.1093/eurheartj/ehae610
Publication status	E-pub ahead of print - 02.09.2024

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Cite this

Desch, S., Zeymer, U., Akin, I., Behnes, M., Duerschmied, D., Rassaf, T., Mahabadi, A. A., Lehmann, R., Eitel, I., Graf, T., Seidler, T., Schuster, A., Thevathasan, T., Skurk, C., Clemmensen, P., Hennersdorf, M., Fichtlscherer, S., Voigt, I., Seyfarth, M., ... Thiele, H. (2024). Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock: 1-Year Results of the ECLS-SHOCK Trial. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae610

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title = "Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock: 1-Year Results of the ECLS-SHOCK Trial",

abstract = "Extracorporeal life support (ECLS) has been increasingly used in the treatment of severe infarct-related cardiogenic shock in the last decade. The randomised ECLS-SHOCK trial demonstrated no benefit of early routine use on 30-day all-cause death. We herein present mid-term results. At 1-year follow-up, there were no significant differences in all-cause or cardiovascular mortality, neurologic outcome, recurrent myocardial infarction, repeat revascularisation and rehospitalisations for heart failure between ECLS and usual medical care.",

author = "Steffen Desch and Uwe Zeymer and Ibrahim Akin and Michael Behnes and Daniel Duerschmied and Tienush Rassaf and Mahabadi, {Amir Abbas} and Ralf Lehmann and Ingo Eitel and Tobias Graf and Tim Seidler and Andreas Schuster and Tharusan Thevathasan and Carsten Skurk and Peter Clemmensen and Marcus Hennersdorf and Stephan Fichtlscherer and Ingo Voigt and Melchior Seyfarth and Stefan John and Sebastian Ewen and Axel Linke and Eike Tigges and Peter Nordbeck and Leonhard Bruch and Christian Jung and Jutta Franz and Philipp Lauten and Marko Noc and Georg Fuernau and Hans-Josef Feistritzer and Janine P{\"o}ss and Eva Kirchhof and Taoufik Ouarrak and Steffen Schneider and Anne Freund and Holger Thiele",

note = "{\textcopyright} The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].",

year = "2024",

month = sep,

day = "2",

doi = "10.1093/eurheartj/ehae610",

language = "English",

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Desch, S, Zeymer, U, Akin, I, Behnes, M, Duerschmied, D, Rassaf, T, Mahabadi, AA, Lehmann, R, Eitel, I, Graf, T, Seidler, T, Schuster, A, Thevathasan, T, Skurk, C, Clemmensen, P, Hennersdorf, M, Fichtlscherer, S, Voigt, I, Seyfarth, M, John, S, Ewen, S, Linke, A, Tigges, E, Nordbeck, P, Bruch, L, Jung, C, Franz, J, Lauten, P, Noc, M, Fuernau, G, Feistritzer, H-J, Pöss, J, Kirchhof, E, Ouarrak, T, Schneider, S, Freund, A & Thiele, H 2024, 'Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock: 1-Year Results of the ECLS-SHOCK Trial', European Heart Journal. https://doi.org/10.1093/eurheartj/ehae610

TY - JOUR

T1 - Routine Extracorporeal Life Support in Infarct-Related Cardiogenic Shock

T2 - 1-Year Results of the ECLS-SHOCK Trial

AU - Desch, Steffen

AU - Zeymer, Uwe

AU - Akin, Ibrahim

AU - Behnes, Michael

AU - Duerschmied, Daniel

AU - Rassaf, Tienush

AU - Mahabadi, Amir Abbas

AU - Lehmann, Ralf

AU - Eitel, Ingo

AU - Graf, Tobias

AU - Seidler, Tim

AU - Schuster, Andreas

AU - Thevathasan, Tharusan

AU - Skurk, Carsten

AU - Clemmensen, Peter

AU - Hennersdorf, Marcus

AU - Fichtlscherer, Stephan

AU - Voigt, Ingo

AU - Seyfarth, Melchior

AU - John, Stefan

AU - Ewen, Sebastian

AU - Linke, Axel

AU - Tigges, Eike

AU - Nordbeck, Peter

AU - Bruch, Leonhard

AU - Jung, Christian

AU - Franz, Jutta

AU - Lauten, Philipp

AU - Noc, Marko

AU - Fuernau, Georg

AU - Feistritzer, Hans-Josef

AU - Pöss, Janine

AU - Kirchhof, Eva

AU - Ouarrak, Taoufik

AU - Schneider, Steffen

AU - Freund, Anne

AU - Thiele, Holger

N1 - © The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].

PY - 2024/9/2

Y1 - 2024/9/2

N2 - Extracorporeal life support (ECLS) has been increasingly used in the treatment of severe infarct-related cardiogenic shock in the last decade. The randomised ECLS-SHOCK trial demonstrated no benefit of early routine use on 30-day all-cause death. We herein present mid-term results. At 1-year follow-up, there were no significant differences in all-cause or cardiovascular mortality, neurologic outcome, recurrent myocardial infarction, repeat revascularisation and rehospitalisations for heart failure between ECLS and usual medical care.

AB - Extracorporeal life support (ECLS) has been increasingly used in the treatment of severe infarct-related cardiogenic shock in the last decade. The randomised ECLS-SHOCK trial demonstrated no benefit of early routine use on 30-day all-cause death. We herein present mid-term results. At 1-year follow-up, there were no significant differences in all-cause or cardiovascular mortality, neurologic outcome, recurrent myocardial infarction, repeat revascularisation and rehospitalisations for heart failure between ECLS and usual medical care.

U2 - 10.1093/eurheartj/ehae610

DO - 10.1093/eurheartj/ehae610

M3 - Journal articles

C2 - 39219338

SN - 0195-668X

JO - European Heart Journal

JF - European Heart Journal

ER -