TY - JOUR
T1 - Role of cytokines in head and neck squamous cell carcinoma
AU - Pries, Ralph
AU - Nitsch, Stefan
AU - Wollenberg, Barbara
PY - 2006/9
Y1 - 2006/9
N2 - Head and neck squamous cell carcinoma is one of the most frequent cancers and standard treatment has only marginally improved the 5-year survival rate of patients with this disease in the last few decades. It is supposed that cytokine alterations in immune, inflammatory and angiogenetic regulatory routes within the head and neck squamous cell carcinoma microenvironment play a critical role in tumor aggressiveness, its response to chemo- and radiation therapies, as well as the development of immune escape mechanisms.
AB - Head and neck squamous cell carcinoma is one of the most frequent cancers and standard treatment has only marginally improved the 5-year survival rate of patients with this disease in the last few decades. It is supposed that cytokine alterations in immune, inflammatory and angiogenetic regulatory routes within the head and neck squamous cell carcinoma microenvironment play a critical role in tumor aggressiveness, its response to chemo- and radiation therapies, as well as the development of immune escape mechanisms.
UR - http://www.scopus.com/inward/record.url?scp=33750046899&partnerID=8YFLogxK
U2 - 10.1586/14737140.6.9.1195
DO - 10.1586/14737140.6.9.1195
M3 - Scientific review articles
C2 - 17020454
AN - SCOPUS:33750046899
SN - 1473-7140
VL - 6
SP - 1195
EP - 1203
JO - Expert Review of Anticancer Therapy
JF - Expert Review of Anticancer Therapy
IS - 9
ER -
