Registration of Histological Serial Sectionings

Jan Modersitzki; Oliver Schmitt; Stefan Wirtz

doi:10.1007/978-3-540-34767-5_3

Registration of Histological Serial Sectionings

Jan Modersitzki, Oliver Schmitt, Stefan Wirtz

Institute of Mathematics

Abstract

Image registration is a fundamental task in today’s medical imaging. Inparticular for histological serial sectioning, where a three-dimensional object is cutinto thin sections for a further microscopic analysis, registration leads to a three di-mensional reconstruction of the sections. This reconstruction enables an explorationof the digitized data in any direction, not only in the cutting direction. In this paper,we describe cutting and reconstruction procedures. For the reconstruction, we uselinear as well as non-linear registration schemes. Moreover, we present some resultsfor a whole brain of a Sprague Dawley rat.

Original language	English
Title of host publication	Mathematical Models for Registration and Applications to Medical Imaging
Editors	Otmar Scherzer
Number of pages	18
Volume	10
Place of Publication	Berlin, Heidelberg
Publisher	Springer Berlin Heidelberg
Publication date	2006
Pages	63-80
ISBN (Print)	978-3-540-25029-6
ISBN (Electronic)	978-3-540-34767-5
DOIs	https://doi.org/10.1007/978-3-540-34767-5_3
Publication status	Published - 2006

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Cite this

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title = "Registration of Histological Serial Sectionings",

abstract = "Image registration is a fundamental task in today{\textquoteright}s medical imaging. Inparticular for histological serial sectioning, where a three-dimensional object is cutinto thin sections for a further microscopic analysis, registration leads to a three di-mensional reconstruction of the sections. This reconstruction enables an explorationof the digitized data in any direction, not only in the cutting direction. In this paper,we describe cutting and reconstruction procedures. For the reconstruction, we uselinear as well as non-linear registration schemes. Moreover, we present some resultsfor a whole brain of a Sprague Dawley rat.",

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Registration of Histological Serial Sectionings. / Modersitzki, Jan; Schmitt, Oliver; Wirtz, Stefan.
Mathematical Models for Registration and Applications to Medical Imaging. ed. / Otmar Scherzer. Vol. 10 Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. p. 63-80 (Mathematics in industry; Vol. 10).

Research output: Chapters in Books/Reports/Conference Proceedings › Chapter › peer-review

TY - CHAP

T1 - Registration of Histological Serial Sectionings

AU - Modersitzki, Jan

AU - Schmitt, Oliver

AU - Wirtz, Stefan

PY - 2006

Y1 - 2006

N2 - Image registration is a fundamental task in today’s medical imaging. Inparticular for histological serial sectioning, where a three-dimensional object is cutinto thin sections for a further microscopic analysis, registration leads to a three di-mensional reconstruction of the sections. This reconstruction enables an explorationof the digitized data in any direction, not only in the cutting direction. In this paper,we describe cutting and reconstruction procedures. For the reconstruction, we uselinear as well as non-linear registration schemes. Moreover, we present some resultsfor a whole brain of a Sprague Dawley rat.

AB - Image registration is a fundamental task in today’s medical imaging. Inparticular for histological serial sectioning, where a three-dimensional object is cutinto thin sections for a further microscopic analysis, registration leads to a three di-mensional reconstruction of the sections. This reconstruction enables an explorationof the digitized data in any direction, not only in the cutting direction. In this paper,we describe cutting and reconstruction procedures. For the reconstruction, we uselinear as well as non-linear registration schemes. Moreover, we present some resultsfor a whole brain of a Sprague Dawley rat.

U2 - 10.1007/978-3-540-34767-5_3

DO - 10.1007/978-3-540-34767-5_3

M3 - Chapter

SN - 978-3-540-25029-6

VL - 10

T3 - Mathematics in industry

SP - 63

EP - 80

BT - Mathematical Models for Registration and Applications to Medical Imaging

A2 - Scherzer, Otmar

PB - Springer Berlin Heidelberg

CY - Berlin, Heidelberg

ER -

Registration of Histological Serial Sectionings

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