Reconstruction is not renovation - The role of remodeling in asthma

Markus Weckmann, Thomas Trian, Brian G.G. Oliver

2 Citations (Scopus)


The chronicity of asthma results not only in persistent lung inflammation but also in changes in structure and composition of this vital organ. These changes are most commonly referred to as remodeling, and include epithelial dysplasia, angiogenesis, changes in the extracellular matrix and increased smooth muscle mass. In this review we summarize recent findings on the contribution of remodeling to the pathological phenotype of asthma. We discuss how and why current treatment (such as corticosteroids) options fail to adequately treat remodeling.

Original languageEnglish
JournalJournal of Asthma and Allergy
Issue number2
Pages (from-to)33-42
Number of pages10
Publication statusPublished - 2009

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


Dive into the research topics of 'Reconstruction is not renovation - The role of remodeling in asthma'. Together they form a unique fingerprint.

Cite this