TY - JOUR
T1 - Rare human IFNG variants
AU - Thye, Thorsten
AU - Ehmen, Christa
AU - Intemann, Christopher D.
AU - Chinbuah, Margaret Amanua
AU - Ziegler, Andreas
AU - Horstmann, Rolf D.
AU - Meyer, Christian G.
PY - 2010/4/1
Y1 - 2010/4/1
N2 - After the identification of the human interferon-gamma (IFNG) variant G54D (c.287G>A, ss105106770) in DNA samples from Ghana, West Africa, systematic mutation screening of IFNG by the LightCycler®-based procedure of high-resolution melting (HRM) revealed additional rare mutations. All variants occurred heterozygously only and were confirmed either by their detection in other individuals and/or by repeated DNA sequencing of independent PCR products.
AB - After the identification of the human interferon-gamma (IFNG) variant G54D (c.287G>A, ss105106770) in DNA samples from Ghana, West Africa, systematic mutation screening of IFNG by the LightCycler®-based procedure of high-resolution melting (HRM) revealed additional rare mutations. All variants occurred heterozygously only and were confirmed either by their detection in other individuals and/or by repeated DNA sequencing of independent PCR products.
UR - http://www.scopus.com/inward/record.url?scp=77952522092&partnerID=8YFLogxK
U2 - 10.1089/jir.2009.0042
DO - 10.1089/jir.2009.0042
M3 - Journal articles
C2 - 20038203
AN - SCOPUS:77952522092
SN - 1079-9907
VL - 30
SP - 219
EP - 222
JO - Journal of Interferon and Cytokine Research
JF - Journal of Interferon and Cytokine Research
IS - 4
ER -
