Random forest classification of large volume structures for visuo-haptic rendering in CT images

André Mastmeyer, Dirk Fortmeier, Heinz Handels


For patient-specific voxel-based visuo-haptic rendering of CT scans of the liver area, the fully automatic segmentation of large volume structures such as skin, soft tissue, lungs and intestine (risk structures) is important. Using a machine learning based approach, several existing segmentations from 10 segmented gold-standard patients are learned by random decision forests individually and collectively. The core of this paper is feature selection and the application of the learned classifiers to a new patient data set. In a leave-some-out cross-validation, the obtained full volume segmentations are compared to the gold-standard segmentations of the untrained patients. The proposed classifiers use a multi-dimensional feature space to estimate the hidden truth, instead of relying on clinical standard threshold and connectivity based methods. The result of our efficient whole-body section classification are multi-label maps with the considered tissues. For visuo-haptic simulation, other small volume structures would have to be segmented additionally. We also take a look into these structures (liver vessels). For an experimental leave-some-out study consisting of 10 patients, the proposed method performs much more efficiently compared to state of the art methods. In two variants of leave-some-out experiments we obtain best mean DICE ratios of 0.79, 0.97, 0.63 and 0.83 for skin, soft tissue, hard bone and risk structures. Liver structures are segmented with DICE 0.93 for the liver, 0.43 for blood vessels and 0.39 for bile vessels.
Original languageEnglish
Title of host publicationMedical Imaging 2016: Image Processing
EditorsMartin A. Styner, Elsa D. Angelini
Number of pages8
Publication date21.03.2016
ISBN (Print)9781510600195
Publication statusPublished - 21.03.2016
EventSPIE Medical Imaging 2016: Image Processing
- San Diego, United States
Duration: 27.02.201603.03.2016


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