Quantitative PCR analysis of different splice forms of NFAT5 revealed specific gene expression in fetal and adult brain

Andreas Dalski*, Hans Joachim Wagner, Eberhard Schwinger, Christine Zühlke

*Corresponding author for this work
13 Citations (Scopus)

Abstract

To investigate sequences or mutations associated with neurodegenerative disorders, we performed analyses for the NFAT5 gene, which is located in the candidate region for the autosomal dominantly inherited spinocerebellar ataxia type 4 (SCA4). PCR based expression analyses detected NFAT5 transcripts with alternative splicing in 27 fetal and adult human tissues. Interestingly, by using quantitative methods on cDNA from fetal and adult human brain a significant difference at the expression level for one splice form could be shown. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
JournalMolecular Brain Research
Volume83
Issue number1-2
Pages (from-to)125-127
Number of pages3
ISSN0169-328X
DOIs
Publication statusPublished - 10.11.2000

Research Areas and Centers

  • Research Area: Medical Genetics

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