Proteinanalyse zur Diagnostik einer Osteitis/Osteomyelitis. Erste Ergebnisse

C. Grimme; T. Gemoll; J. Habermann; K. Seide; U. J. Gerlach

doi:10.1007/s10039-011-1830-0

Proteinanalyse zur Diagnostik einer Osteitis/Osteomyelitis. Erste Ergebnisse

Translated title of the contribution: Analysis of protein for the diagnosis of osteitis/osteomyelitis. Initial results

C. Grimme^*, T. Gemoll, J. Habermann, K. Seide, U. J. Gerlach

^*Corresponding author for this work

Clinic of Surgery

Berufsgenossenschaftliches Unfallkrankenhaus (Trauma Hospital) Hamburg

Abstract

A certain preoperative diagnosis of osteomyelitis is difficult. The anamnesis, physical examination, laboratory medicine and diagnostic radiography are of utter importance. Postoperative bacteriological and histopathological analyses are confirmatory. The aim of this research study was the analysis of bone protein assays to detect a significant difference between acutely infected and no longer acutely infected bone. The first results demonstrate similar protein expression patterns between acute and no longer acute osteomyelitis with only 31 significantly different regulated protein spots. In summary after standardized sample recovery and preparation it is possible to obtain a well-defined prediction of acute and no longer acute osteomyelitis and healthy bone.

Translated title of the contribution	Analysis of protein for the diagnosis of osteitis/osteomyelitis. Initial results
Original language	German
Journal	Trauma und Berufskrankheit
Volume	14
Issue number	1
Pages (from-to)	5-7
Number of pages	3
ISSN	1436-6274
DOIs	https://doi.org/10.1007/s10039-011-1830-0
Publication status	Published - 01.03.2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s10039-011-1830-0

Cite this

@article{c92ba08964714f57b6b778cd5e0134b2,

title = "Proteinanalyse zur Diagnostik einer Osteitis/Osteomyelitis. Erste Ergebnisse",

abstract = "A certain preoperative diagnosis of osteomyelitis is difficult. The anamnesis, physical examination, laboratory medicine and diagnostic radiography are of utter importance. Postoperative bacteriological and histopathological analyses are confirmatory. The aim of this research study was the analysis of bone protein assays to detect a significant difference between acutely infected and no longer acutely infected bone. The first results demonstrate similar protein expression patterns between acute and no longer acute osteomyelitis with only 31 significantly different regulated protein spots. In summary after standardized sample recovery and preparation it is possible to obtain a well-defined prediction of acute and no longer acute osteomyelitis and healthy bone.",

author = "C. Grimme and T. Gemoll and J. Habermann and K. Seide and Gerlach, {U. J.}",

year = "2012",

month = mar,

day = "1",

doi = "10.1007/s10039-011-1830-0",

language = "Deutsch",

volume = "14",

pages = "5--7",

journal = "Trauma und Berufskrankheit",

issn = "1436-6274",

number = "1",

}

TY - JOUR

T1 - Proteinanalyse zur Diagnostik einer Osteitis/Osteomyelitis. Erste Ergebnisse

AU - Grimme, C.

AU - Gemoll, T.

AU - Habermann, J.

AU - Seide, K.

AU - Gerlach, U. J.

PY - 2012/3/1

Y1 - 2012/3/1

N2 - A certain preoperative diagnosis of osteomyelitis is difficult. The anamnesis, physical examination, laboratory medicine and diagnostic radiography are of utter importance. Postoperative bacteriological and histopathological analyses are confirmatory. The aim of this research study was the analysis of bone protein assays to detect a significant difference between acutely infected and no longer acutely infected bone. The first results demonstrate similar protein expression patterns between acute and no longer acute osteomyelitis with only 31 significantly different regulated protein spots. In summary after standardized sample recovery and preparation it is possible to obtain a well-defined prediction of acute and no longer acute osteomyelitis and healthy bone.

AB - A certain preoperative diagnosis of osteomyelitis is difficult. The anamnesis, physical examination, laboratory medicine and diagnostic radiography are of utter importance. Postoperative bacteriological and histopathological analyses are confirmatory. The aim of this research study was the analysis of bone protein assays to detect a significant difference between acutely infected and no longer acutely infected bone. The first results demonstrate similar protein expression patterns between acute and no longer acute osteomyelitis with only 31 significantly different regulated protein spots. In summary after standardized sample recovery and preparation it is possible to obtain a well-defined prediction of acute and no longer acute osteomyelitis and healthy bone.

UR - http://www.scopus.com/inward/record.url?scp=84860889295&partnerID=8YFLogxK

U2 - 10.1007/s10039-011-1830-0

DO - 10.1007/s10039-011-1830-0

M3 - Zeitschriftenaufsätze

AN - SCOPUS:84860889295

SN - 1436-6274

VL - 14

SP - 5

EP - 7

JO - Trauma und Berufskrankheit

JF - Trauma und Berufskrankheit

IS - 1

ER -

Proteinanalyse zur Diagnostik einer Osteitis/Osteomyelitis. Erste Ergebnisse

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this