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Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

D. A. Akkad, P. Jagiello, P. Szyld, R. Goedde, S. Wieczorek, W. L. Gross, J. T. Epplen*

*Corresponding author for this work

Abstract

We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.

Original languageEnglish
JournalInternational Journal of Immunogenetics
Volume33
Issue number1
Pages (from-to)59-61
Number of pages3
ISSN1744-3121
DOIs
Publication statusPublished - 02.2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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