Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

D. A. Akkad; P. Jagiello; P. Szyld; R. Goedde; S. Wieczorek; W. L. Gross; J. T. Epplen

doi:10.1111/j.1744-313X.2006.00568.x

Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

D. A. Akkad, P. Jagiello, P. Szyld, R. Goedde, S. Wieczorek, W. L. Gross, J. T. Epplen^*

^*Corresponding author for this work

Clinic of Rheumatology

Ruhr-University Bochum

34 Citations (Scopus)

Abstract

We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.

Original language	English
Journal	International Journal of Immunogenetics
Volume	33
Issue number	1
Pages (from-to)	59-61
Number of pages	3
ISSN	1744-3121
DOIs	https://doi.org/10.1111/j.1744-313X.2006.00568.x
Publication status	Published - 02.2006

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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10.1111/j.1744-313X.2006.00568.x

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Akkad, D. A., Jagiello, P., Szyld, P., Goedde, R., Wieczorek, S., Gross, W. L., & Epplen, J. T. (2006). Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups. International Journal of Immunogenetics, 33(1), 59-61. https://doi.org/10.1111/j.1744-313X.2006.00568.x

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title = "Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups",

abstract = "We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.",

author = "Akkad, {D. A.} and P. Jagiello and P. Szyld and R. Goedde and S. Wieczorek and Gross, {W. L.} and Epplen, {J. T.}",

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Akkad, DA, Jagiello, P, Szyld, P, Goedde, R, Wieczorek, S, Gross, WL & Epplen, JT 2006, 'Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups', International Journal of Immunogenetics, vol. 33, no. 1, pp. 59-61. https://doi.org/10.1111/j.1744-313X.2006.00568.x

Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups. / Akkad, D. A.; Jagiello, P.; Szyld, P. et al.
In: International Journal of Immunogenetics, Vol. 33, No. 1, 02.2006, p. 59-61.

Research output: Journal Articles › Journal articles › Research › peer-review

TY - JOUR

T1 - Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

AU - Akkad, D. A.

AU - Jagiello, P.

AU - Szyld, P.

AU - Goedde, R.

AU - Wieczorek, S.

AU - Gross, W. L.

AU - Epplen, J. T.

PY - 2006/2

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N2 - We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.

AB - We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.

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U2 - 10.1111/j.1744-313X.2006.00568.x

DO - 10.1111/j.1744-313X.2006.00568.x

M3 - Journal articles

C2 - 16426246

AN - SCOPUS:33645072733

SN - 1744-3121

VL - 33

SP - 59

EP - 61

JO - International Journal of Immunogenetics

JF - International Journal of Immunogenetics

IS - 1

ER -

Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

Abstract

Research Areas and Centers

UN SDGs

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