Prognostic value of the MIB-1 labeling index for central neurocytomas

Dirk Rades; Steven E. Schild; Fabian Fehlauer

doi:10.1212/01.WNL.0000115392.21898.E3

Prognostic value of the MIB-1 labeling index for central neurocytomas

Dirk Rades^*, Steven E. Schild, Fabian Fehlauer

^*Corresponding author for this work

Department of Radiotherapy

86 Citations (Scopus)

Abstract

Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004).

Original language	English
Journal	Neurology
Volume	62
Issue number	6
Pages (from-to)	987-989
Number of pages	3
ISSN	0028-3878
DOIs	https://doi.org/10.1212/01.WNL.0000115392.21898.E3
Publication status	Published - 23.03.2004

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10.1212/01.WNL.0000115392.21898.E3

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title = "Prognostic value of the MIB-1 labeling index for central neurocytomas",

abstract = "Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3\% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004).",

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T1 - Prognostic value of the MIB-1 labeling index for central neurocytomas

AU - Rades, Dirk

AU - Schild, Steven E.

AU - Fehlauer, Fabian

PY - 2004/3/23

Y1 - 2004/3/23

N2 - Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004).

AB - Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004).

UR - https://www.scopus.com/pages/publications/1842509957

U2 - 10.1212/01.WNL.0000115392.21898.E3

DO - 10.1212/01.WNL.0000115392.21898.E3

M3 - Journal articles

C2 - 15037708

AN - SCOPUS:1842509957

SN - 0028-3878

VL - 62

SP - 987

EP - 989

JO - Neurology

JF - Neurology

IS - 6

ER -

Prognostic value of the MIB-1 labeling index for central neurocytomas

Abstract

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