Prior knowledge is essential for the beneficial effect of targeted memory reactivation during sleep

Sabine Groch, Thomas Schreiner, Björn Rasch, Reto Huber, Ines Wilhelm*

*Corresponding author for this work
20 Citations (Scopus)

Abstract

Prior knowledge speeds up system consolidation and accelerates integration of newly acquired memories into existing neocortical knowledge networks. By using targeted memory reactivations, we demonstrate that prior knowledge is also essential for successful reactivation and consolidation of memories during sleep, both on the behavioral and oscillatory level (i.e., theta and fast spindle activity). Thus, prior knowledge is a prerequisite for new memories to enter processes of system consolidation during sleep.

Original languageEnglish
Article number39763
JournalScientific Reports
Volume7
ISSN2045-2322
DOIs
Publication statusPublished - 04.01.2017

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 2.23-08 Human Cognitive and Systems Neuroscience
  • 2.23-03 Experimental and Theoretical Network Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  • SDG 3 - Good Health and Well-being

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  • CRC 654: Plasticity and Sleep

    Born, J. (Speaker, Coordinator), Verleger, R. (Principal Investigator (PI)), Witt, K. (Principal Investigator (PI)), Gais, S. (Principal Investigator (PI)), Kimmig, H. (Principal Investigator (PI)), Backhaus, J. (Principal Investigator (PI)), Junghanns, K. (Principal Investigator (PI)), Marshall, L. (Principal Investigator (PI)), Martinetz, T. (Principal Investigator (PI)), Mölle, M. (Principal Investigator (PI)), Deuschl, G. (Principal Investigator (PI)), Mehdorn, H. M. (Principal Investigator (PI)), Volkmann, J. (Principal Investigator (PI)), Claussen, J. C. (Principal Investigator (PI)), Göder, R. (Principal Investigator (PI)), Anders, S. (Principal Investigator (PI)), Binkofski, F. (Principal Investigator (PI)), Büchel, C. (Principal Investigator (PI)), Ehrlich, I. (Principal Investigator (PI)), Baving, L. (Principal Investigator (PI)), Prehn-Kristensen, A. (Principal Investigator (PI)), Bartsch, T. (Principal Investigator (PI)), Sirota, A. (Principal Investigator (PI)), Münte, T. (Principal Investigator (PI)), Heldmann, M. (Principal Investigator (PI)), Diekelmann, S. (Principal Investigator (PI)), Rauss, K. (Principal Investigator (PI)), Sato, T. (Principal Investigator (PI)), Krägeloh-Mann, I. (Principal Investigator (PI)), Wilke, M. (Principal Investigator (PI)), Hallschmid, M. (Principal Investigator (PI)), Schmid, S. (Principal Investigator (PI)), Kern, W. (Principal Investigator (PI)), Perras, B. (Principal Investigator (PI)), Poets, C. F. (Principal Investigator (PI)), Sayk, F. (Principal Investigator (PI)), Oster, H. (Principal Investigator (PI)), Lehnert, H. (Principal Investigator (PI)), Baier, P. C. (Principal Investigator (PI)), Oltmanns, K. (Principal Investigator (PI)), Fritsche, A. (Principal Investigator (PI)), Preissl, H. (Principal Investigator (PI)), Ernst, M. (Principal Investigator (PI)), Zabel, P. (Principal Investigator (PI)), Solbach, W. (Principal Investigator (PI)), Kalies, K. (Principal Investigator (PI)), Westermann, J. (Principal Investigator (PI)), Rose-John, S. (Principal Investigator (PI)), Lange, T. (Principal Investigator (PI)), Rammensee, H. G. (Principal Investigator (PI)), Autenrieth, S. E. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)) & Ehlers, M. (Principal Investigator (PI))

    01.01.05 → 31.12.17

    Project: DFG Joint Research › DFG Collaborative Research Centers (CRC)

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