Predictive Validity of a Screening Instrument for the Risk of Non–Return to Work in Patients With Internal Diseases

Marco Streibelt*, Matthias Bethge, Thomas Gross, Klaus Herrmann, Ferman Ustaoglu, Christoph Reichel

*Corresponding author for this work
9 Citations (Scopus)


Objective To test the predictive validity of the SIMBO (Screening-Instrument zur Feststellung des Bedarfs an medizinisch-beruflich orientierten Maßnahmen in der medizinischen Rehabilitation [Screening Instrument for the Access to Work-Related Multimodal Rehabilitation]; total score ranges from 0 to 100 points) in patients with internal diseases in a rehabilitation setting. Design Prospective multicenter study. Setting Inpatient rehabilitation centers. Participants Patients (N=1366) aged 18 to 65 years with internal diseases. Interventions Multimodal rehabilitation programs. Main Outcome Measures The primary outcome was occurrence of a critical return-to-work (RTW) event during the follow-up period. Receiver operating characteristic analyses were performed. Sensitivity, specificity, and positive predictive values were calculated for each disease group using the cutoff score of 27 points. Results A total of 1366 patients with neoplasms (n=203); endocrine, nutritional, and metabolic diseases (n=355); and diseases of the circulatory (n=470), respiratory (n=255), and digestive (n=83) systems were included. Between 9.9% and 40.6% of the patients reported critical RTW events during the 3-month follow-up period. The area under the curve was between .849 (.754–.923) and .903 (.846–.959). Sensitivity and specificity ranged from 65.6% to 92.9% and from 80.4% to 89.9%, respectively. The positive predictive values were between 40.4% and 77.8%. Conclusions The risk score SIMBO predicts short-term RTW problems after rehabilitation in patients with internal diseases. The cutoff of 27 points was confirmed as a reasonable threshold.

Original languageEnglish
JournalArchives of Physical Medicine and Rehabilitation
Issue number5
Pages (from-to)989-996
Number of pages8
Publication statusPublished - 01.05.2017

Research Areas and Centers

  • Research Area: Center for Population Medicine and Public Health (ZBV)


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