TY - JOUR
T1 - Predicting survival after whole-brain irradiation for cerebral metastases in patients with cancer of the bladder
AU - Rades, Dirk
AU - Dziggel, Liesa
AU - Manig, Lisa
AU - Janssen, Stefan
AU - Khoa, Mai Trong
AU - Duong, Vuong Ngoc
AU - Khiem, Vu Huu
AU - Schild, Steven E.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Background/Aim: This study aimed to create a predictive tool for estimating the remaining lifespan of patients after whole-brain irradiation (WBI) for cerebral metastases from bladder cancer. Patients and Methods: In 34 of these patients clinical parameters were analyzed for survival including age at start of WBI, gender, Karnofsky score, number of cerebral metastases and involvement of extra-cranial sites of metastasis. Results: Involvement of extra-cranial sites (14%) and Karnofsky score (9%) showed the greatest difference regarding 6-month survival and were considered for the tool. Points were assigned based on the following: no involvement of extra-cranial sites=1 point, involvement of extra-cranial sites=0 points, Karnofsky score =70=1 point, Karnofsky score =60=0 points. Patients’scores were 0, 1 or 2 points with 6-month survival rates of 13%, 27% and 50%, respectively. Conclusion: Based on two clinical parameters, a tool was developed that may help estimate the lifespan of patients irradiated for cerebral metastases from bladder cancer.
AB - Background/Aim: This study aimed to create a predictive tool for estimating the remaining lifespan of patients after whole-brain irradiation (WBI) for cerebral metastases from bladder cancer. Patients and Methods: In 34 of these patients clinical parameters were analyzed for survival including age at start of WBI, gender, Karnofsky score, number of cerebral metastases and involvement of extra-cranial sites of metastasis. Results: Involvement of extra-cranial sites (14%) and Karnofsky score (9%) showed the greatest difference regarding 6-month survival and were considered for the tool. Points were assigned based on the following: no involvement of extra-cranial sites=1 point, involvement of extra-cranial sites=0 points, Karnofsky score =70=1 point, Karnofsky score =60=0 points. Patients’scores were 0, 1 or 2 points with 6-month survival rates of 13%, 27% and 50%, respectively. Conclusion: Based on two clinical parameters, a tool was developed that may help estimate the lifespan of patients irradiated for cerebral metastases from bladder cancer.
UR - http://www.scopus.com/inward/record.url?scp=85048636677&partnerID=8YFLogxK
U2 - 10.21873/invivo.11285
DO - 10.21873/invivo.11285
M3 - Journal articles
C2 - 29695570
AN - SCOPUS:85048636677
SN - 0258-851X
VL - 32
SP - 633
EP - 636
JO - In Vivo
JF - In Vivo
IS - 3
ER -