Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer

Dirk Rades; Liesa Dziggel; Samer G Hakim; Volker Rudat; Stefan Janssen; Ngo Thuy Trang; Mai Trong Khoa; Tobias Bartscht

Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer

Dirk Rades, Liesa Dziggel, Samer G Hakim, Volker Rudat, Stefan Janssen, Ngo Thuy Trang, Mai Trong Khoa, Tobias Bartscht

Abstract

AIM: Patients with cerebral metastases from head and neck cancer are not common. This study aimed to create an instrument for estimating survival in this particular group of patients.

PATIENTS AND METHODS: Survival was significantly influenced by Eastern Cooperative Oncology Group (ECOG) performance score, number of cerebral lesions and extracranial metastatic disease. These characteristics were included in our score.

RESULTS: Scoring was based on 6-month survival data: ECOG 0-1=1 point, ECOG 2-3=0 points, 1-3 cerebral lesions=1 point, ≥4 cerebral lesions=0 points, lack of extracranial metastases=1 point, and presence of extracranial metastases=0 points. Addition of these points for each patient resulted in 0-3 points. Three groups were built comprising 0-1, 2 and 3 points. Six-month survival rates for these groups were 0%, 50% and 100%, respectively.

CONCLUSION: This new instrument guides physicians in choosing optimal irradiation programs for patients with cerebral metastases from head-and-neck cancer.

Original language	English
Journal	In vivo (Athens, Greece)
Volume	29
Issue number	5
Pages (from-to)	525-8
Number of pages	4
ISSN	0258-851X
Publication status	Published - 12.09.2015

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Cite this

@article{5a0941a3ec2d4872b93789425626404b,

title = "Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer",

abstract = "AIM: Patients with cerebral metastases from head and neck cancer are not common. This study aimed to create an instrument for estimating survival in this particular group of patients.PATIENTS AND METHODS: Survival was significantly influenced by Eastern Cooperative Oncology Group (ECOG) performance score, number of cerebral lesions and extracranial metastatic disease. These characteristics were included in our score.RESULTS: Scoring was based on 6-month survival data: ECOG 0-1=1 point, ECOG 2-3=0 points, 1-3 cerebral lesions=1 point, ≥4 cerebral lesions=0 points, lack of extracranial metastases=1 point, and presence of extracranial metastases=0 points. Addition of these points for each patient resulted in 0-3 points. Three groups were built comprising 0-1, 2 and 3 points. Six-month survival rates for these groups were 0\%, 50\% and 100\%, respectively.CONCLUSION: This new instrument guides physicians in choosing optimal irradiation programs for patients with cerebral metastases from head-and-neck cancer.",

author = "Dirk Rades and Liesa Dziggel and Hakim, \{Samer G\} and Volker Rudat and Stefan Janssen and Trang, \{Ngo Thuy\} and Khoa, \{Mai Trong\} and Tobias Bartscht",

year = "2015",

month = sep,

day = "12",

language = "English",

volume = "29",

pages = "525--8",

journal = "In vivo (Athens, Greece)",

issn = "0258-851X",

publisher = "International Institute of Anticancer Research",

number = "5",

}

TY - JOUR

T1 - Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer

AU - Rades, Dirk

AU - Dziggel, Liesa

AU - Hakim, Samer G

AU - Rudat, Volker

AU - Janssen, Stefan

AU - Trang, Ngo Thuy

AU - Khoa, Mai Trong

AU - Bartscht, Tobias

PY - 2015/9/12

Y1 - 2015/9/12

N2 - AIM: Patients with cerebral metastases from head and neck cancer are not common. This study aimed to create an instrument for estimating survival in this particular group of patients.PATIENTS AND METHODS: Survival was significantly influenced by Eastern Cooperative Oncology Group (ECOG) performance score, number of cerebral lesions and extracranial metastatic disease. These characteristics were included in our score.RESULTS: Scoring was based on 6-month survival data: ECOG 0-1=1 point, ECOG 2-3=0 points, 1-3 cerebral lesions=1 point, ≥4 cerebral lesions=0 points, lack of extracranial metastases=1 point, and presence of extracranial metastases=0 points. Addition of these points for each patient resulted in 0-3 points. Three groups were built comprising 0-1, 2 and 3 points. Six-month survival rates for these groups were 0%, 50% and 100%, respectively.CONCLUSION: This new instrument guides physicians in choosing optimal irradiation programs for patients with cerebral metastases from head-and-neck cancer.

AB - AIM: Patients with cerebral metastases from head and neck cancer are not common. This study aimed to create an instrument for estimating survival in this particular group of patients.PATIENTS AND METHODS: Survival was significantly influenced by Eastern Cooperative Oncology Group (ECOG) performance score, number of cerebral lesions and extracranial metastatic disease. These characteristics were included in our score.RESULTS: Scoring was based on 6-month survival data: ECOG 0-1=1 point, ECOG 2-3=0 points, 1-3 cerebral lesions=1 point, ≥4 cerebral lesions=0 points, lack of extracranial metastases=1 point, and presence of extracranial metastases=0 points. Addition of these points for each patient resulted in 0-3 points. Three groups were built comprising 0-1, 2 and 3 points. Six-month survival rates for these groups were 0%, 50% and 100%, respectively.CONCLUSION: This new instrument guides physicians in choosing optimal irradiation programs for patients with cerebral metastases from head-and-neck cancer.

M3 - Journal articles

C2 - 26359409

SN - 0258-851X

VL - 29

SP - 525

EP - 528

JO - In vivo (Athens, Greece)

JF - In vivo (Athens, Greece)

IS - 5

ER -

Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer

Abstract

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