Prävention und Behandlung der Kachexie: Bewegungs- und Ernährungstherapie

Translated title of the contribution: Prevention and treatment of cachexia: Exercise and nutritional therapy

B. Wilms, S. M. Schmid*, K. Luley, J. Wiskemann, H. Lehnert

*Corresponding author for this work


Background: Cachexia is a multifactorial and complex syndrome characterized by progressive functional impairment and ongoing loss in quality of life, which lead to a deterioration of the prognosis for affected patients. The prevalence of cachexia can be very high and is up to 80 % in patients with malignant tumors. Objective: The aim of the study was to assess the relevance of exercise and nutrition in the prevention and therapy of cachexia. Methods: An evaluation of the current literature on exercise and nutritional therapy in patients with cachexia or with advanced stage diseases where a high prevalence of cachexia is probable, was carried out. Results: There is a lack of scientific evidence for the benefits of exercise in cachexia. A major problem of relevant studies was that cachexia was frequently not defined according to valid criteria; however, data indicate a benefit of exercise training in patients with advanced diseases associated with a high prevalence of cachexia. A solely nutritional intervention and dietary counselling seem to be of minimal benefit. The administration of omega 3 fatty acids is controversially discussed. Conclusion: Although there is a lack of data on the effects of exercise and nutritional therapy in cachexia, there is evidence for the benefits. The present data indicate the necessity for the use of a multimodal treatment including exercise, nutritional and pharmacological therapy in cachexia. There is a great necessity for prospective studies

Translated title of the contributionPrevention and treatment of cachexia: Exercise and nutritional therapy
Original languageGerman
Issue number10
Pages (from-to)971-977
Number of pages7
Publication statusPublished - 01.10.2016

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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