Polymyalgia rheumatica: Myalgisches Syndrom oder okkulte Vaskulitis?

Translated title of the contribution: Polymyalgia rheumatica: Myalgic syndrome or occult vasculitis?

B. Hellmich*, W. L. Gross

*Corresponding author for this work
4 Citations (Scopus)


Polymyalgia rheumatica (PMR) is a chronic inflammatory disorder of unknown etiology which typically presents with symmetric myalgias in the shoulder and pelvic girdles. Other clinical signs include the rapid onset of symptoms and the almost exclusive manifestation in the elderly population. In around 20% of cases, PMR is associated with giant cell arteritis (GCA). However, new imaging techniques suggest that the prevalence of subclinical GCA (e. g. aortitis) in PMR is probably higher. Acute phase reactants like erythrocyte sedimentation rate and c-reactive protein are usually elevated. Myalgias are accompanied by synovitis and bursitis of the large proximal joints and can be visualized by ultrasound or magnetic resonance imaging. While the diagnosis of GCA can be verified by temporal artery biopsy, pathognomonic findings for PMR like specific autoantibodies are lacking. Typical for PMR is the rapid response to corticosteroids. Usually the therapy needs to be continued for at least 2 years. Due to adverse events in many cases a corticosteroid saving therapy like methotrexate is needed.

Translated title of the contributionPolymyalgia rheumatica: Myalgic syndrome or occult vasculitis?
Original languageGerman
Issue number11
Pages (from-to)1233-1244
Number of pages12
Publication statusPublished - 11.2005

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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