Optical coherence tomography (OCT) is now state of the art in ophthalmology. Other medical departments, such as otolaryngology, could also benefit from this imaging modality. Polarization is a property which is a benefit to conventional OCT. It can be used in particular to detect birefringent tissue layers. To evaluate possible OCT applications in Ear, Nose and Throat (ENT) department, a fiber-based polarization-sensitive OCT (PSOCT) is used to measure human ex-vivo tissue biopsies. A total of 58 samples from 20 different tissues were measured. The measurements show that small biopsies lose their birefringent property, this leads to the assumption that tissue-matrices lose tension and molecular order. Larger samples show phase retardation and are used to detect different birefringent layers of tissue. We also show a method of verifying cancer diagnosis by displaying the tissue layer structure. As a conclusion, PS-OCT may improve cancer diagnosis in ENT.
|Title of host publication||Student Conference Medical Engineering Science 2013|
|Editors||T. M. Buzug|
|Number of pages||4|
|Place of Publication||Lübeck|
|Publication status||Published - 2013|
|Event||Student Conference 2013 - Lübeck, Germany|
Duration: 13.03.2013 → 14.03.2013