Physical and FEM Simulation of Microprobe Insertion into Rat Brain

A. E. Olamat; N. Nkemasong; B. M. Pohl; U. G. Hofmann

Physical and FEM Simulation of Microprobe Insertion into Rat Brain

A. E. Olamat, N. Nkemasong, B. M. Pohl, U. G. Hofmann

Institute of Signal Processing

Abstract

In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

Original language	English
Number of pages	5
Publication status	Published - 01.11.2010
Event	European COMSOL Conference 2010 - the Palais des congrès de Versailles, Paris, France Duration: 17.11.2010 → 19.11.2010

Conference

Conference	European COMSOL Conference 2010
Country/Territory	France
City	Paris
Period	17.11.10 → 19.11.10

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

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Olamat, A. E., Nkemasong, N., Pohl, B. M., & Hofmann, U. G. (2010). Physical and FEM Simulation of Microprobe Insertion into Rat Brain. Paper presented at European COMSOL Conference 2010, Paris, France. https://www.researchgate.net/profile/Ulrich_Hofmann3/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain/links/0fcfd50cb765926a42000000/Physical-and-FEM-simulation-of-microprobe-insertion-into-rat-brain.pdf

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abstract = "In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals. ",

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Olamat, AE, Nkemasong, N, Pohl, BM & Hofmann, UG 2010, 'Physical and FEM Simulation of Microprobe Insertion into Rat Brain', Paper presented at European COMSOL Conference 2010, Paris, France, 17.11.10 - 19.11.10. <https://www.researchgate.net/profile/Ulrich_Hofmann3/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain/links/0fcfd50cb765926a42000000/Physical-and-FEM-simulation-of-microprobe-insertion-into-rat-brain.pdf>

TY - CONF

T1 - Physical and FEM Simulation of Microprobe Insertion into Rat Brain

AU - Olamat, A. E.

AU - Nkemasong, N.

AU - Pohl, B. M.

AU - Hofmann, U. G.

PY - 2010/11/1

Y1 - 2010/11/1

N2 - In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

AB - In order to investigate theimplantation of microprobes into brain tissue, wedeveloped a finite-element and a physical modelto replace real biological tissue for mechanicaltesting. Penetrating forces of a tungsten indenterinto a layered structure was investigated withdifferent indentation speeds. Numerical andphysical model are in good correspondence toeach other and reproduce measured brainelasticity (15kPa) and dimpling effects followedby rupturing of the top layer well. We suggestfor future mechanical evaluation of brain probesto first utilize model structures before sacrificinganimals.

UR - https://www.researchgate.net/publication/230603382_Physical_and_FEM_simulation_of_microprobe_insertion_into_rat_brain

M3 - Conference Papers

T2 - European COMSOL Conference 2010

Y2 - 17 November 2010 through 19 November 2010

ER -

Physical and FEM Simulation of Microprobe Insertion into Rat Brain

Abstract

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UN SDGs

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