Pemphigoid gestationis: Treatment with immunoapheresis

Stefan Wöhrl*, Alexandra Geusau, Franz Karlhofer, Kurt Derfler, Georg Stingl, Detlef Zillikens

*Corresponding author for this work
32 Citations (Scopus)


Background: Pemphigoid (herpes) gestationis is a rare blistering disease of pregnancy. Topical and systemic corticosteroids and antihistamines are usually sufficient for treatment. Case report: A patient suffering from severe, therapy-resistant pemphigoid gestationis was successfully treated with the additional use of six sessions of immunoapheresis. Systemic corticosteroids could be tapered and serum autoantibody levels to bullous pemphigoid antigen 2 (BPAG2 = BP180) significantly dropped during this treatment. Conclusion: Immunoapheresis represents a helpful therapeutic option with few side effects for severe cases of pemphigoid gestationis, unresponsive to conventional treatment.

Original languageEnglish
JournalJDDG - Journal of the German Society of Dermatology
Issue number2
Pages (from-to)126-130
Number of pages5
Publication statusPublished - 01.02.2003


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