Patients' interpersonal problems as moderators of depression outcomes in a randomized controlled trial comparing mindfulness-based cognitive therapy and a group version of the cognitive-behavioral analysis system of psychotherapy in chronic depression

Thomas Probst*, Elisabeth Schramm, Thomas Heidenreich, Jan Philipp Klein, Johannes Michalak

*Corresponding author for this work
1 Citation (Scopus)

Abstract

Objectives: Interpersonal problems were examined as moderators of depression outcomes between mindfulness-based cognitive therapy (MBCT) and cognitive behavioral analysis system of psychotherapy (CBASP) in patients with chronic depression. Methods: Patients received treatment-as-usual and, in addition, were randomized to 8-weeks of MBCT (n = 34) or 8-weeks of CBASP (n = 34). MBCT and CBASP were given in a group format. The Hamilton depression rating scale (HAM-D) was the primary and the Beck Depression Inventory (BDI-II) the secondary outcome. The subscales of the Inventory of interpersonal problems (IIP-32) were moderators. Multilevel models were performed. Results: Higher scores on the “vindictive/self-centered” subscale were associated with a better outcome in MBCT than in CBASP (HAM-D: p <.01; BDI-II: p <.01). Higher scores on the “nonassertive” subscale were associated with a better outcome in CBASP than in MBCT (HAM-D: p <.01; BDI-II: p <.01). Conclusions: If these results can be replicated in larger trials, MBCT should be preferred to CBASP in chronically depressed patients being vindictive/self-centered, whereas CBASP should be preferred to MBCT in chronically depressed patients being nonassertive.

Original languageEnglish
JournalJournal of Clinical Psychology
Volume76
Issue number7
Pages (from-to)1241-1254
Number of pages14
ISSN0021-9762
DOIs
Publication statusPublished - 01.07.2020

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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