Patient mood and neuropsychological outcome after laparoscopic and conventional colectomy

M. Gameiro, W. Eichler, O. Schwandner, R. Bouchard, J. Schön, P. Schmucker, H. P. Bruch, Michael Hüppe*

*Corresponding author for this work
8 Citations (Scopus)


The study was designed to compare patients after laparoscopic and conventional colectomy with regard to early postoperative mood, cognitive function, and neurocognitive variables S100β and neuron-specific enolase (NSE). Forty-five laparoscopic and 25 open colectomies were enrolled into the prospective study. Outcome measurements were positive and negative postoperative mood (BSKE), neuropsychological tests (Trail-Making Test; word reproduction; Stroop Test), and serum biochemical parameters (S100β NSE). Following laparoscopic procedure, patients described significantly better positive mood (P ≤ .05), tended to require less time in the Trail-Making Test and Stroop Test, and had lower postoperative serum concentrations of S100β compared to conventional colectomy patients (P ≤ .01). The current results revealed several group differences, which, in their entirety, seem to represent a more beneficial outcome after laparoscopic colonic surgery.

Original languageEnglish
JournalSurgical Innovation
Issue number3
Pages (from-to)171-178
Number of pages8
Publication statusPublished - 2008

Research Areas and Centers

  • Research Area: Luebeck Integrated Oncology Network (LION)


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