Pathogens in Sepsis: Gram-Negative Bacterial PAMPs and PRRs

Andra Schromm*, Christian Alexander, Thomas Gutsmann, Jörg Andrä, Cordula Stamme

*Corresponding author for this work

Abstract

This chapter contains sections titled:

Introduction

Pathogen‐associated Molecular Pattern (PAMP) Molecules of GNB

The LPS‐activated TLR4/MD‐2‐signaling system: Central PRR Signaling Pathways and Negative Regulatory Factors

Endotoxic Activity of Enterobacterial LPS is determined by Physico‐chemical Properties

Modulation of Biological Activity of LPS

Therapeutic Approaches

Acknowledgments

References
Original languageEnglish
Title of host publicationSepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care
Number of pages32
PublisherWiley-VCH Verlag GmbH & Co. KGaA
Publication date25.05.2009
Pages77-108
ISBN (Print)9783527319350
DOIs
Publication statusPublished - 25.05.2009

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