Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging

K. Lüdtke-Buzug; S. Biederer; T. F. Sattel; T. Knopp; T. M. Buzug

doi:10.1007/978-3-642-03887-7_63

Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging

K. Lüdtke-Buzug^*, S. Biederer, T. F. Sattel, T. Knopp, T. M. Buzug

^*Corresponding author for this work

Institute of Medical Engineering

13 Citations (Scopus)

Abstract

During the last few years, nanosized super-paramagnetic materials based on iron-oxide, so called SPIOs, became more and more interesting due to an increasing variety of applications from cancer therapy to contrast enhancement in magnetic resonance imaging. Superparamagnetic iron-oxide based contrast agents like Resovist™ had been widely established in radiological imaging of the reticuloendothelial system. Recently, a novel imaging technique called magnetic particle imaging (MPI) has been proposed for determination of the spatial distribution of iron-oxide nanoparticles. In first publications of MPI, Resovist™ plays a key role. Unfortunately, however, Resovist™ has been withdrawn by Bayer Schering Pharma in the end of 2008. Therefore, the analysis of an acceptable surrogate agent is presented in this paper. By means of dynamical light scattering and magnetic particle spectroscopy it will be demonstrated that dextrancoated iron oxide nanoparticles can be synthesized with similar particle size distribution and analogous magnetic properties compared to the carboxydextran-coated Resovist™.

Original language	English
Title of host publication	World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany
Editors	Olaf Dössel, Wolfgang C. Schlegel
Number of pages	4
Volume	25
Publisher	Springer Berlin Heidelberg
Publication date	2009
Edition	8
Pages	226-229
ISBN (Print)	978-3-642-03886-0
ISBN (Electronic)	978-3-642-03887-7
DOIs	https://doi.org/10.1007/978-3-642-03887-7_63
Publication status	Published - 2009
Event	World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging - Munich , Germany Duration: 07.09.2009 → 12.09.2009 Conference number: 81644

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SDG 9 Industry, Innovation, and Infrastructure

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Academic Focus: Biomedical Engineering

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10.1007/978-3-642-03887-7_63

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Lüdtke-Buzug, K., Biederer, S., Sattel, T. F., Knopp, T., & Buzug, T. M. (2009). Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. In O. Dössel, & W. C. Schlegel (Eds.), World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany (8 ed., Vol. 25, pp. 226-229). (IFMBE Proceedings; Vol. 25/8). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-03887-7_63

Lüdtke-Buzug, K. ; Biederer, S. ; Sattel, T. F. et al. / Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. editor / Olaf Dössel ; Wolfgang C. Schlegel. Vol. 25 8. ed. Springer Berlin Heidelberg, 2009. pp. 226-229 (IFMBE Proceedings).

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title = "Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging",

abstract = "During the last few years, nanosized super-paramagnetic materials based on iron-oxide, so called SPIOs, became more and more interesting due to an increasing variety of applications from cancer therapy to contrast enhancement in magnetic resonance imaging. Superparamagnetic iron-oxide based contrast agents like Resovist{\texttrademark} had been widely established in radiological imaging of the reticuloendothelial system. Recently, a novel imaging technique called magnetic particle imaging (MPI) has been proposed for determination of the spatial distribution of iron-oxide nanoparticles. In first publications of MPI, Resovist{\texttrademark} plays a key role. Unfortunately, however, Resovist{\texttrademark} has been withdrawn by Bayer Schering Pharma in the end of 2008. Therefore, the analysis of an acceptable surrogate agent is presented in this paper. By means of dynamical light scattering and magnetic particle spectroscopy it will be demonstrated that dextrancoated iron oxide nanoparticles can be synthesized with similar particle size distribution and analogous magnetic properties compared to the carboxydextran-coated Resovist{\texttrademark}.",

author = "K. L{\"u}dtke-Buzug and S. Biederer and Sattel, \{T. F.\} and T. Knopp and Buzug, \{T. M.\}",

note = "Copyright: Copyright 2021 Elsevier B.V., All rights reserved.; World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging ; Conference date: 07-09-2009 Through 12-09-2009",

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Lüdtke-Buzug, K, Biederer, S, Sattel, TF, Knopp, T & Buzug, TM 2009, Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. in O Dössel & W C. Schlegel (eds), World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. 8 edn, vol. 25, IFMBE Proceedings, vol. 25/8, Springer Berlin Heidelberg, pp. 226-229, World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging, Munich , Bavaria, Germany, 07.09.09. https://doi.org/10.1007/978-3-642-03887-7_63

Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. / Lüdtke-Buzug, K.; Biederer, S.; Sattel, T. F. et al.
World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. ed. / Olaf Dössel; Wolfgang C. Schlegel. Vol. 25 8. ed. Springer Berlin Heidelberg, 2009. p. 226-229 (IFMBE Proceedings; Vol. 25/8).

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging

AU - Lüdtke-Buzug, K.

AU - Biederer, S.

AU - Sattel, T. F.

AU - Knopp, T.

AU - Buzug, T. M.

N1 - Conference code: 81644

PY - 2009

Y1 - 2009

N2 - During the last few years, nanosized super-paramagnetic materials based on iron-oxide, so called SPIOs, became more and more interesting due to an increasing variety of applications from cancer therapy to contrast enhancement in magnetic resonance imaging. Superparamagnetic iron-oxide based contrast agents like Resovist™ had been widely established in radiological imaging of the reticuloendothelial system. Recently, a novel imaging technique called magnetic particle imaging (MPI) has been proposed for determination of the spatial distribution of iron-oxide nanoparticles. In first publications of MPI, Resovist™ plays a key role. Unfortunately, however, Resovist™ has been withdrawn by Bayer Schering Pharma in the end of 2008. Therefore, the analysis of an acceptable surrogate agent is presented in this paper. By means of dynamical light scattering and magnetic particle spectroscopy it will be demonstrated that dextrancoated iron oxide nanoparticles can be synthesized with similar particle size distribution and analogous magnetic properties compared to the carboxydextran-coated Resovist™.

AB - During the last few years, nanosized super-paramagnetic materials based on iron-oxide, so called SPIOs, became more and more interesting due to an increasing variety of applications from cancer therapy to contrast enhancement in magnetic resonance imaging. Superparamagnetic iron-oxide based contrast agents like Resovist™ had been widely established in radiological imaging of the reticuloendothelial system. Recently, a novel imaging technique called magnetic particle imaging (MPI) has been proposed for determination of the spatial distribution of iron-oxide nanoparticles. In first publications of MPI, Resovist™ plays a key role. Unfortunately, however, Resovist™ has been withdrawn by Bayer Schering Pharma in the end of 2008. Therefore, the analysis of an acceptable surrogate agent is presented in this paper. By means of dynamical light scattering and magnetic particle spectroscopy it will be demonstrated that dextrancoated iron oxide nanoparticles can be synthesized with similar particle size distribution and analogous magnetic properties compared to the carboxydextran-coated Resovist™.

UR - https://www.scopus.com/pages/publications/77949902194

U2 - 10.1007/978-3-642-03887-7_63

DO - 10.1007/978-3-642-03887-7_63

M3 - Conference contribution

SN - 978-3-642-03886-0

VL - 25

T3 - IFMBE Proceedings

SP - 226

EP - 229

BT - World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany

A2 - Dössel, Olaf

A2 - C. Schlegel, Wolfgang

PB - Springer Berlin Heidelberg

T2 - World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging

Y2 - 7 September 2009 through 12 September 2009

ER -

Lüdtke-Buzug K, Biederer S, Sattel TF, Knopp T, Buzug TM. Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. In Dössel O, C. Schlegel W, editors, World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. 8 ed. Vol. 25. Springer Berlin Heidelberg. 2009. p. 226-229. (IFMBE Proceedings). doi: 10.1007/978-3-642-03887-7_63

Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging

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