TY - JOUR
T1 - Paroxysmal hemichorea after streptococcal infectionclinical and diagnostic findings
AU - Härtel, Christoph
AU - Schepermann, Kathrin
AU - Schilling, Stefan
AU - Petersen, Dirk
AU - Eckerle, Susanne
AU - Sperner, Jürgen
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2003
Y1 - 2003
N2 - Chorea is characterized by abnormal hyperkinetic movements which may be a clinical symptom in a wide array of neurological disorders. This report describes the case of a 7- year-old boy who developed a paroxysmal, rightsided hemichorea three weeks after a throat infection. In correlation to the clinical findings, the area of the left putamen presented with a minimal lesion in diffusion weighted Magnetic resonances imaging which was not further evident two weeks later. Corresponding flour deoxy glucose positron emisson tomograpy showed an increased glucose uptake of the left lentiform nucleus and left frontocentral cortex. Given the serological evidence of streptococcal infection as specific trigger, this case report illustrates not only the importance of neuroimaging data in the differential diagnosis of chorea but also the potential pathophysiological role of immune-mediated reactions as etiological factor.
AB - Chorea is characterized by abnormal hyperkinetic movements which may be a clinical symptom in a wide array of neurological disorders. This report describes the case of a 7- year-old boy who developed a paroxysmal, rightsided hemichorea three weeks after a throat infection. In correlation to the clinical findings, the area of the left putamen presented with a minimal lesion in diffusion weighted Magnetic resonances imaging which was not further evident two weeks later. Corresponding flour deoxy glucose positron emisson tomograpy showed an increased glucose uptake of the left lentiform nucleus and left frontocentral cortex. Given the serological evidence of streptococcal infection as specific trigger, this case report illustrates not only the importance of neuroimaging data in the differential diagnosis of chorea but also the potential pathophysiological role of immune-mediated reactions as etiological factor.
UR - http://www.scopus.com/inward/record.url?scp=85013605125&partnerID=8YFLogxK
U2 - 10.1055/s-0035-1557179
DO - 10.1055/s-0035-1557179
M3 - Journal articles
AN - SCOPUS:85013605125
SN - 1304-2580
VL - 1
SP - 103
EP - 106
JO - Journal of Pediatric Neurology
JF - Journal of Pediatric Neurology
IS - 2
ER -