Ovarian cancer and Mayer-Rokitansky-Kuster-Hauser syndrome

Andreas Kavallaris*, Khalid H. Sait, Ehab Abu Marar, Rafat Abu Shakra, Klaus Diedrich

*Corresponding author for this work


A 48-year-old woman with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, right kidney aplasia, a pelvic-abdominal mass, and an elevated CA-125 level underwent bilateral salpingo-oophorectomy, omentectomy, and debulking for a presumed ovarian carcinoma. Intraoperative findings included a pelvic tumor on the surface of both ovaries. Pathological examination revealed a poorly differentiated ovarian carcinoma, mixed type, mainly of transitional and serous types, with minor components of clear cell and mucinous patterns. A stage III ovarian epithelial carcinoma, mixed type was diagnosed. The patient was treated with Paclitaxel and Carboplatin and was asymptomatic 24 months postoperatively. Rarely, ovarian carcinoma may be associated with MRKH syndrome.

Original languageEnglish
JournalGynecological Surgery
Issue number2
Pages (from-to)197-199
Number of pages3
Publication statusPublished - 01.05.2011


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