Optimizing the polarization matrix for ex situ dynamic nuclear polarization

Christian Ludwig, Ildefonso Marin-Montesinos, Martin G. Saunders, Ulrich L. Günther

21 Citations (Scopus)


(Figure Presented) Although recent advances in dynamic nuclear polarization techniques have boosted the otherwise low sensitivity of NMR spectroscopy, the efficiency of the hyperpolarization process depends on the composition of the polarization matrix, in particular on the contact between the radical and the target molecule and the capability of the matrix to transfer polarization through spin diffusion. A concept for optimal matrix design is presented, applied to obtain two-dimensional heterocorrelated spectra of small drug-like molecules in 1-2 min after 90 min of hyperpolarization.

Original languageEnglish
JournalJournal of the American Chemical Society
Issue number8
Pages (from-to)2508-2509
Number of pages2
Publication statusPublished - 24.02.2010

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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