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Nuclear topoisomerase II activity changes during HL-60 leukemic cell differentiation: Alterations in drug sensitivity and ph dependency
Frank Gieseler
*
, Fritz Boege,
Harald Biersack
, Birgit Spohn, Michael Clark, Klaus Wilms
*
Corresponding author for this work
Clinic of Internal Medicine I
University of Würzburg
6
Citations (Scopus)
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Dive into the research topics of 'Nuclear topoisomerase II activity changes during HL-60 leukemic cell differentiation: Alterations in drug sensitivity and ph dependency'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Cellular Differentiation
100%
Topoisomerase
100%
DNA Topoisomerase
100%
DNA Gyrase
100%
Cytotoxicity
33%
Dimethyl Sulfoxide
33%
Medicine and Dentistry
Drug Sensitivity
100%
DNA Topoisomerase (ATP Hydrolysing)
100%
Topoisomerase
75%
Dimethyl Sulfoxide
25%
HL-60 Cell Line
25%
Gyrase Inhibitor
25%
Pharmacology, Toxicology and Pharmaceutical Science
Etoposide
100%
DNA Topoisomerase (ATP Hydrolysing)
100%
DNA Topoisomerase
75%
Dimethyl Sulfoxide
25%
Cytotoxicity
25%