Nosokomiale infektionen bei neugeborenen. Wo stehen wir in Deutschland?

Translated title of the contribution: Nosocomial infections in neonates. What is the situation in Germany?

C. Geffers, S. Haller, G. Heller, L. Gortner, W. Göpel, C. Bührer*

*Corresponding author for this work
8 Citations (Scopus)


Background. Outbreaks of nosocomial infections in neonates have recently received broad media interest. Objectives. Data on nosocomial infections in German neonatal intensive care units are presented. Material and methods. The available epidemiological data, mostly based on the NEO-KISS (hospital infection surveillance system) surveillance system were analyzed. Results. Nosocomial infections (e.g. sepsis, pneumonia and necrotizing enterocolitis) affect approximately 44% of preterm infants <500 g birth weight, 34% of infants with birth weights 500-999 g and 12% of infants with birth weights 1,000-1,499 g, with sepsis (78%) dominating over pneumonia (13%) and necrotizing enterocolitis (9%). Device use and understaffing have emerged as important risk factors in addition to low birth weight and gestational age. The gap in hazard ratios between central and peripheral catheters has almost disappeared (6.18 and 5.97, respectively). Understaffing (>5% below target) is linked with an almost 50% increase in the risk of catheter-associated sepsis (odds ratio 1.47). Coagulase-negative staphylococci are cultured in more than 50% of bloodstream positive sepsis cases while bacteria with multiple antibiotic resistance are recovered in only 3.4% of cases. To date, no cases of carbapenem-resistant gram-negative sepsis have been observed in the German neonatal intensive care units under surveillance. Depending on the time interval (14-90 days) used for defining an outbreak, the number of outbreaks in neonatal intensive care units per year varies from 26 to 61. Conclusion. More detailed information on neonatal nosocomial infections will be available following incorporation of the NEO-KISS module into the EuroNeoNet quality improvement initiative (2012). Furthermore, data concerning the use of antibiotics and microbial resistance patterns have been collected since 2013.

Translated title of the contributionNosocomial infections in neonates. What is the situation in Germany?
Original languageGerman
JournalMonatsschrift fur Kinderheilkunde
Issue number5
Pages (from-to)385-393
Number of pages9
Publication statusPublished - 05.2014

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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