TY - JOUR
T1 - Normal values for the full visual field, corrected for ageand reaction time, using semiautomated kinetic testing on the octopus 900 perimeter
AU - Grobbel, Julia
AU - Dietzsch, Janko
AU - Johnson, Chris A.
AU - Vonthein, Reinhard
AU - Stingl, Katarina
AU - Weleber, Richard G.
AU - Schiefer, Ulrich
PY - 2016/3
Y1 - 2016/3
N2 - Purpose:To determine normal values of the visual field (VF), corrected for age and reaction time (RT) for semiautomated kinetic perimetry (SKP) on the Octopus 900 perimeter, create a model describing the age-dependency of these values, and assess test–retest reliability for each isopter. Methods:Eighty-six eyes of 86 ophthalmologically healthy subjects (age 11–79 years, 34 males, 52 females) underwent full-field kinetic perimetry with the Octopus 900 instrument. Stimulus size, luminance, velocity, meridional angle, subject age, and their interactions, were used to create a smooth multiple regression mathematical model (V/4e, III/4e, I/4e, I/3e, I/2e, I/1e, and I/1a isopters). Fourteen subjects (2 from each of 7 age groups) were evaluated on three separate sessions to assess test–retest reliability of the isopters. Reaction time (RT) was tested by presenting 12 designated RT-vectors between 10° and 20° within the seeing areas for the III/4e isopter (stimulus velocity, 3°/second). Four RT- vectors were presented at the nasal (0° or 180°), superotemporal (45°), and inferior (270°) meridians. Results:The model fit was excellent (r2= 0.94). The test–retest variability was less than 5°, and the median decrease in this deviation attributed to aging, per decade, for all age groups and for all stimulus sizes was 0.8°. No significant learning effect was observed for any age group or isopter. Conclusion:Age-corrected and RT-corrected normative threshold values for full-field kinetic perimetry can be adequately described by a smooth multiple linear regression mathematical model. Translational Relevance:A description of the entire kinetic VF is useful for assessing a full characterization of VF sensitivity, determining function losses associated with ocular and neurologic diseases, and for providing a more comprehensive analysis of structure–function relationships.
AB - Purpose:To determine normal values of the visual field (VF), corrected for age and reaction time (RT) for semiautomated kinetic perimetry (SKP) on the Octopus 900 perimeter, create a model describing the age-dependency of these values, and assess test–retest reliability for each isopter. Methods:Eighty-six eyes of 86 ophthalmologically healthy subjects (age 11–79 years, 34 males, 52 females) underwent full-field kinetic perimetry with the Octopus 900 instrument. Stimulus size, luminance, velocity, meridional angle, subject age, and their interactions, were used to create a smooth multiple regression mathematical model (V/4e, III/4e, I/4e, I/3e, I/2e, I/1e, and I/1a isopters). Fourteen subjects (2 from each of 7 age groups) were evaluated on three separate sessions to assess test–retest reliability of the isopters. Reaction time (RT) was tested by presenting 12 designated RT-vectors between 10° and 20° within the seeing areas for the III/4e isopter (stimulus velocity, 3°/second). Four RT- vectors were presented at the nasal (0° or 180°), superotemporal (45°), and inferior (270°) meridians. Results:The model fit was excellent (r2= 0.94). The test–retest variability was less than 5°, and the median decrease in this deviation attributed to aging, per decade, for all age groups and for all stimulus sizes was 0.8°. No significant learning effect was observed for any age group or isopter. Conclusion:Age-corrected and RT-corrected normative threshold values for full-field kinetic perimetry can be adequately described by a smooth multiple linear regression mathematical model. Translational Relevance:A description of the entire kinetic VF is useful for assessing a full characterization of VF sensitivity, determining function losses associated with ocular and neurologic diseases, and for providing a more comprehensive analysis of structure–function relationships.
UR - http://www.scopus.com/inward/record.url?scp=84979292241&partnerID=8YFLogxK
U2 - 10.1167/tvst.5.2.5
DO - 10.1167/tvst.5.2.5
M3 - Journal articles
AN - SCOPUS:84979292241
SN - 2164-2591
VL - 5
JO - Translational Vision Science and Technology
JF - Translational Vision Science and Technology
IS - 2
M1 - 5
ER -