TY - JOUR
T1 - Neuropsychological and neurophysiological findings in individuals suspected to be at risk for schizophrenia
T2 - Preliminary results from the Basel early detection of psychosis study - Früherkennung von Psychosen (FEPSY)
AU - Gschwandtner, Ute
AU - Aston, J.
AU - Borgwardt, S.
AU - Drewe, M.
AU - Feinendegen, C.
AU - Lacher, D.
AU - Lanzarone, A.
AU - Stieglitz, R. D.
AU - Riecher-Rössler, A.
PY - 2003/8/1
Y1 - 2003/8/1
N2 - Objective: Our study aims to establish a scientific basis for the very early detection of patients at risk for schizophrenia during the nonspecific prodromal phase of the disorder and to predict its outbreak. Method: A multidomain approach is used. After screening, approved psychopathological, neurophysiological, neuropsychotogical and neuroradiological investigations are used to assess a sample of individuals suspected to be at risk for schizophrenia. Results: Neuropsychological and fine motor functioning tests as well as eye movement measurements showed statistically significant differences (P < 0.01) between individuals suspected to be at risk for schizophrenia and healthy controls. Conclusion: Individuals suspected to be at risk for schizophrenia show specific impairments in various investigations including neuropsychological and fine motor functioning tests as well as eye movement measurements. A set of methods sensitive to even subtle changes in normal functioning may prove useful in predicting the subsequent outbreak of schizophrenia.
AB - Objective: Our study aims to establish a scientific basis for the very early detection of patients at risk for schizophrenia during the nonspecific prodromal phase of the disorder and to predict its outbreak. Method: A multidomain approach is used. After screening, approved psychopathological, neurophysiological, neuropsychotogical and neuroradiological investigations are used to assess a sample of individuals suspected to be at risk for schizophrenia. Results: Neuropsychological and fine motor functioning tests as well as eye movement measurements showed statistically significant differences (P < 0.01) between individuals suspected to be at risk for schizophrenia and healthy controls. Conclusion: Individuals suspected to be at risk for schizophrenia show specific impairments in various investigations including neuropsychological and fine motor functioning tests as well as eye movement measurements. A set of methods sensitive to even subtle changes in normal functioning may prove useful in predicting the subsequent outbreak of schizophrenia.
UR - http://www.scopus.com/inward/record.url?scp=0038384017&partnerID=8YFLogxK
U2 - 10.1034/j.1600-0447.2003.00157.x
DO - 10.1034/j.1600-0447.2003.00157.x
M3 - Journal articles
C2 - 12823173
AN - SCOPUS:0038384017
SN - 0001-690X
VL - 108
SP - 152
EP - 155
JO - Acta Psychiatrica Scandinavica
JF - Acta Psychiatrica Scandinavica
IS - 2
ER -