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Abstract
Objective: To assess the neurodevelopmental health of children born after intracytoplasmatic sperm injection (ICSI). Design: Prospective controlled blinded study. Setting: Tertiary care center. Patient(s): A total of 276 term-born singletons conceived by ICSI and 273 matched spontaneously conceived (SC) singletons at the age of 5.5 years. Main Outcome Measure(s): Neuromotor development assessed by a detailed neurologic examination, including the standardized motor test MOT 4-6, and emotional/behavioral development and intelligence assessed with the Kaufman-Assessment Battery for Children. Result(s): There were no significant differences between ICSI children and control children regarding the neurologic examination, motor skills, emotional/behavioral development, and intelligence. Conclusion(s): The ICSI children born at term develop normally, similar to SC children.
Original language | English |
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Journal | Fertility and Sterility |
Volume | 91 |
Issue number | 1 |
Pages (from-to) | 125-132 |
Number of pages | 8 |
ISSN | 0015-0282 |
DOIs | |
Publication status | Published - 01.01.2009 |
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Dive into the research topics of 'Neuromotor development and mental health at 5.5 years of age of singletons born at term after intracytoplasmatic sperm injection ICSI: results of a prospective controlled single-blinded study in Germany'. Together they form a unique fingerprint.Projects
- 1 Finished
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ICSI-2: Prospektive, kontrollierte Untersuchung von Kindern im Alter von 5 bis 6 Jahren, die nach einer intrazytoplasmatischen Spermieninjektion (ICSI) geboren worden sind
Ludwig, M. (Principal Investigator (PI)), Diedrich, K. (Associated Staff), Katalinic, A. (Associated Staff) & Thyen, U. (Associated Staff)
01.01.04 → 31.12.11
Project: DFG Projects › DFG Individual Projects