Abstract
Obsessive-compulsive disorder (OCD) is a common psychiatric illness characterized by intrusive, repetitive thoughts and behaviours which cause marked distress. During the last decade, different models were developed for the pathophysiology of the obsessive-compulsive-disorder. Three different neurobiological models are introduced in this article: 1. model of dysfunctional kortikostriatal circuitry, 2. amygdalocentric model, 3. neurochemical model. These models don't exclude themselves mutually but supplement themselves and should ideally be integrated into a bio-psycho-social concept. Such increased understanding of the neurobiology can be translated into better diagnosis and treatment for those patients who suffer from obsessive-compulsive-disorder.
Translated title of the contribution | Neurobiological aspects of the etiology and pathophysiology of obsessive-compulsive disorders |
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Original language | German |
Journal | PPmP Psychotherapie Psychosomatik Medizinische Psychologie |
Volume | 50 |
Issue number | 11 |
Pages (from-to) | 428-434 |
Number of pages | 7 |
ISSN | 0937-2032 |
DOIs | |
Publication status | Published - 2000 |
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)