Obsessive-compulsive disorder (OCD) is a common psychiatric illness characterized by intrusive, repetitive thoughts and behaviours which cause marked distress. During the last decade, different models were developed for the pathophysiology of the obsessive-compulsive-disorder. Three different neurobiological models are introduced in this article: 1. model of dysfunctional kortikostriatal circuitry, 2. amygdalocentric model, 3. neurochemical model. These models don't exclude themselves mutually but supplement themselves and should ideally be integrated into a bio-psycho-social concept. Such increased understanding of the neurobiology can be translated into better diagnosis and treatment for those patients who suffer from obsessive-compulsive-disorder.
|Translated title of the contribution
|Neurobiological aspects of the etiology and pathophysiology of obsessive-compulsive disorders
|PPmP Psychotherapie Psychosomatik Medizinische Psychologie
|Number of pages
|Published - 2000
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)