Neurobiologische aspekte zur atiologie und pathophysiologie der zwangsstorung

Translated title of the contribution: Neurobiological aspects of the etiology and pathophysiology of obsessive-compulsive disorders

A. Kordon*, F. Hohagen

*Corresponding author for this work
8 Citations (Scopus)

Abstract

Obsessive-compulsive disorder (OCD) is a common psychiatric illness characterized by intrusive, repetitive thoughts and behaviours which cause marked distress. During the last decade, different models were developed for the pathophysiology of the obsessive-compulsive-disorder. Three different neurobiological models are introduced in this article: 1. model of dysfunctional kortikostriatal circuitry, 2. amygdalocentric model, 3. neurochemical model. These models don't exclude themselves mutually but supplement themselves and should ideally be integrated into a bio-psycho-social concept. Such increased understanding of the neurobiology can be translated into better diagnosis and treatment for those patients who suffer from obsessive-compulsive-disorder.

Translated title of the contributionNeurobiological aspects of the etiology and pathophysiology of obsessive-compulsive disorders
Original languageGerman
JournalPPmP Psychotherapie Psychosomatik Medizinische Psychologie
Volume50
Issue number11
Pages (from-to)428-434
Number of pages7
ISSN0937-2032
DOIs
Publication statusPublished - 2000

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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