Neurobiologie und Wirkmodelle zu Psychedelika

Understanding the therapeutic potential of psychedelics in mental illness necessitates an exploration of their underlying mechanisms of action across various levels. This includes psychopharmacological, neurobiological, neurosystemic, and psychotherapeutic dimensions. In addition to traditional neurochemical and receptor physiology considerations, this article delves into neurobiological insights regarding emotion regulation, perceptual processing, and the default mode network modulation induced by psychedelics. These insights provide a foundation for formulating hypotheses on the neurodynamic information processings involved. Furthermore, the transition to psychotherapeutic effects is discussed, emphasizing the integration of neurobiological and psychotherapeutic perspectives. Adopting a comprehensive view of psychedelics' effects can inform the development of targeted psychotherapeutic interventions or establish a psychotherapeutic framework for incorporating psychedelic use in therapeutic settings.